Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 1.00 |
| ▸ | PGR | P06401 | 6/20 | 1.00 |
| ▸ | AR | P10275 | 4/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Al-43 SCHEMBL29364100 | 1.00 | NR3C1 (1.00) | NR3C1PGRAR | |
| Al-43 SCHEMBL4172433 | 1.00 | NR3C1 (1.00) | NR3C1PGRAR | |
| Al-43 SCHEMBL7132239 | 0.93 | NR3C1 (0.85) | NR3C1PGRAR | |
| SCHEMBL6294343 | 0.91 | NR3C1 (1.00) | NR3C1PGRAR | |
| SCHEMBL4170535 | 0.91 | NR3C1 (1.00) | NR3C1PGRAR | |
| SCHEMBL4172432 | 0.91 | NR3C1 (1.00) | NR3C1PGRAR | |
| SCHEMBL4186130 | 0.91 | NR3C1 (0.83) | NR3C1PGRAR | |
| SCHEMBL6291135 | 0.90 | NR3C1 (1.00) | NR3C1PGRAR | |
| SCHEMBL4179264 | 0.90 | NR3C1 (1.00) | NR3C1PGRAR | |
| SCHEMBL4170282 | 0.90 | NR3C1 (1.00) | NR3C1PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608216-B2 | Preparing biaryl atropisomers; chirality transfer from stereogenic center of secondary alcohol to biaryl stereogenic axis via regioselective intramolecular migration | ABBOTT LABORATORIES | 2003-08-19 | — | — | US | claimed |
| US-20030073844-A1 | Process for the preparation of chiral glucocorticoid receptor agents | ABBOTT LABORATORIES | 2003-04-17 | — | — | US | claimed |
| WO-2003002548-A1 | A PROCESS FOR THE PREPARATION OF CHIRAL GLUCOCORTICOID RECEPTOR AGENTS | ABBOTT LABORATORIES (US) | 2003-01-09 | — | — | WO | claimed |
| US-6608216-B2 | Preparing biaryl atropisomers; chirality transfer from stereogenic center of secondary alcohol to biaryl stereogenic axis via regioselective intramolecular migration | ABBOTT LABORATORIES | 2003-08-19 | — | — | US | disclosed |
| US-20030073844-A1 | Process for the preparation of chiral glucocorticoid receptor agents | ABBOTT LABORATORIES | 2003-04-17 | — | — | US | disclosed |
| WO-2003002548-A1 | A PROCESS FOR THE PREPARATION OF CHIRAL GLUCOCORTICOID RECEPTOR AGENTS | ABBOTT LABORATORIES (US) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073844-A1 | Process for the preparation of chiral glucocorticoid receptor agents | NR3C1, NR3C2, MC2R | NR3C1 1/4885PGR 286/4885AR 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.