Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877661 | 0.93 | ALDH1A1 (0.52) | ALDH1A1HTTCRHBPCRHR2MCOLN3 | |
| SCHEMBL176523 | 0.93 | ALDH1A1 (0.52) | ALDH1A1HTTCRHBPCRHR2MCOLN3 | |
| Hydrochloric Acid SCHEMBL7936029 | 0.90 | ALDH1A1 (0.50) | ALDH1A1HTTCRHBPCRHR2MCOLN3 | |
| SCHEMBL7627478 | 0.90 | ALDH1A1 (0.50) | ALDH1A1HTTCRHBPCRHR2MCOLN3 | |
| SCHEMBL6273763 | 0.84 | ALDH1A1 (0.46) | ALDH1A1HTTCRHBPCRHR2MCOLN3 | |
| Formic Acid SCHEMBL20660413 | 0.84 | ALDH1A1 (0.46) | ALDH1A1HTTCRHBPCRHR2MCOLN3 | |
| Amantadine SCHEMBL8710832 | 0.82 | LMNA (0.56) | ALDH1A1HTTCRHBPCRHR2MCOLN3 | |
| SCHEMBL16038530 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL31074189 | 0.79 | — | — | |
| Trifluoroacetic Acid SCHEMBL6384678 | 0.79 | ALDH1A1 (0.42) | ALDH1A1HTTCRHBPCRHR2MCOLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927219-B2 | N-alkyl-adamantyl triazinyl benzamide derivatives | PFIZER INC. (US) | 2005-08-09 | — | — | US | disclosed |
| US-20030144293-A1 | N-alkyl-adamantyl triazinyl benzamide derivatives | PFIZER INC. | 2003-07-31 | — | — | US | disclosed |
| WO-2003042190-A1 | N-ALKYL-ADAMANTYL DERIVATIVES AS P2X7-RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2003-05-22 | — | — | WO | disclosed |
| EP-1310493-A1 | N-adamantylalkyl benzamide derivates as p2x7-receptor antagonists | Pfizer Products Inc. (US) | 2003-05-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144293-A1 | N-alkyl-adamantyl triazinyl benzamide derivatives | AIFM1, BAD, BID | ALDH1A1 156/4885HTT 2104/4885CRHBP 4798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.