Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL560884 | 0.82 | TDP1 (0.41) | TDP1 | |
| SCHEMBL3551089 | 0.79 | — | — | |
| SCHEMBL18412739 | 0.79 | — | — | |
| SCHEMBL12870189 | 0.79 | — | — | |
| SCHEMBL16415632 | 0.75 | TDP1 (0.35) | TDP1 | |
| SCHEMBL9540645 | 0.75 | TDP1 (0.35) | TDP1 | |
| SCHEMBL4036597 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL12027144 | 0.71 | — | — | |
| SCHEMBL1926199 | 0.71 | — | — | |
| SCHEMBL14411125 | 0.70 | TDP1 (0.36) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6953785-B2 | Estra-1,3,5(10)-triene derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2005-10-11 | — | — | US | disclosed |
| US-20030216362-A1 | Estra-1,3,5 (10)-triene derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-11-20 | — | — | US | disclosed |
| EP-1284272-A1 | ESTRA-1,3,5(10)-TRIENE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-02-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216362-A1 | Estra-1,3,5 (10)-triene derivatives | STS, SULT1E1, SULT1A1 | TDP1 3624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.