Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL560884 | 0.86 | TDP1 (0.41) | TDP1CYP1A2CYP2D6 | |
| SCHEMBL16415632 | 0.79 | TDP1 (0.35) | TDP1CYP1A2CYP2D6 | |
| Ether SCHEMBL4867180 | 0.77 | TDP1 (0.53) | TDP1CYP1A2 | |
| SCHEMBL12417282 | 0.76 | — | — | |
| SCHEMBL15699400 | 0.76 | — | — | |
| SCHEMBL6290748 | 0.75 | TDP1 (0.32) | TDP1 | |
| SCHEMBL14411126 | 0.75 | THRB (0.30) | — | |
| SCHEMBL10041845 | 0.74 | — | — | |
| SCHEMBL9887527 | 0.74 | — | — | |
| SCHEMBL13311568 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079774-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. | 2018-03-22 | — | — | US | disclosed |
| EP-2825286-A1 | AMINE TREATING PROCESS FOR ACID GAS SEPARATION USING BLENDS OF AMINES AND ALKYLOXYAMINES | ExxonMobil Research and Engineering Company (US) | 2015-01-21 | — | — | EP | disclosed |
| US-20130243676-A1 | AMINE TREATING PROCESS FOR ACID GAS SEPARATION USING BLENDS OF AMINES AND ALKYLOXYAMINES | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2013-09-19 | — | — | US | disclosed |
| WO-2013138443-A1 | AMINE TREATING PROCESS FOR ACID GAS SEPARATION USING BLENDS OF AMINES AND ALKYLOXYAMINES | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2013-09-19 | — | — | WO | disclosed |
| WO-1993010883-A1 | LEAN ACID GAS ENRICHMENT WITH SELECTIVE HINDERED AMINES | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1993-06-10 | — | — | WO | disclosed |
| EP-0087856-B1 | A PROCESS FOR THE REMOVAL OF H2S FROM GASEOUS MIXTURES USING DIAMINOETHERS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1986-02-26 | — | — | EP | disclosed |
| US-4405583-A | Process for selective removal of H2 S from mixtures containing H22 using di-severely sterically hindered secondary aminoethers | EXXON RESEARCH AND ENGINEERING CO. (US) | 1983-09-20 | — | — | US | disclosed |
| EP-0087856-A1 | A process for the removal of H2S from gaseous mixtures using diaminoethers | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1983-09-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079774-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | PNP, NUDT1, NT5C3B | TDP1 480/4885CYP1A2 2032/4885CYP2D6 1864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.