Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.58 |
| ▸ | QPCT | Q16769 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | NOS1 | P29475 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4902296 | 0.93 | TBXAS1 (0.68) | KMT2ATBXAS1NOS1ALDH1A1 | |
| SCHEMBL12045305 | 0.82 | TBXAS1 (0.84) | KMT2ATBXAS1QPCTMEN1ATM | |
| Hydrochloric Acid SCHEMBL9996074 | 0.81 | TBXAS1 (0.82) | KMT2ATBXAS1QPCTMEN1ATM | |
| Hydrochloric Acid SCHEMBL2529362 | 0.79 | MEN1 (0.85) | KMT2ATBXAS1QPCTMEN1ATM | |
| SCHEMBL12045307 | 0.78 | TBXAS1 (0.82) | KMT2ATBXAS1MEN1NOS1ALDH1A1 | |
| SCHEMBL8638819 | 0.77 | CACNA1B (0.77) | KMT2ATBXAS1QPCTMEN1ATM | |
| SCHEMBL10476929 | 0.77 | TBXAS1 (0.79) | KMT2ATBXAS1MEN1NOS1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9996079 | 0.77 | TBXAS1 (0.79) | KMT2ATBXAS1MEN1ATMNOS1 | |
| SCHEMBL1927388 | 0.75 | KMT2A (0.71) | KMT2ATBXAS1QPCTNOS1ALDH1A1 | |
| SCHEMBL15075252 | 0.75 | KMT2A (1.00) | KMT2AQPCTMEN1NOS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6979693-B2 | Pyrazole derivatives-p38 MAP kinase inhibitors | SYNTEX (U.S.A.) LLC (US) | 2005-12-27 | — | — | US | disclosed |
| US-6444696-B1 | 1-ARYL OR HETEROARYL SUBSTITUTED 5-AMINO-4 CARBONYLPYRAZOLE DERIVATIVES; ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) LLC | 2002-09-03 | — | — | US | disclosed |
| US-6376527-B1 | ANTIINFLAMMATORY AGENTS; AUTOIMMUNE DISEASES | SYNTEX (U.S.A.) LLC | 2002-04-23 | — | — | US | disclosed |
| US-6316466-B1 | Pyrazole derivatives P-38 MAP kinase inhibitors | SYNTEX (U.S.A.) LLC | 2001-11-13 | — | — | US | disclosed |