Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NOS1 | P29475 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6292244 | 0.93 | KMT2A (0.60) | TBXAS1ALDH1A1KMT2ANOS1 | |
| SCHEMBL1566298 | 0.82 | TBXAS1 (0.71) | TBXAS1ALDH1A1KDM4EMAPK1LTA4H | |
| SCHEMBL10370478 | 0.82 | TBXAS1 (1.00) | TBXAS1ALDH1A1KDM4EMAPK1LTA4H | |
| Hydrochloric Acid SCHEMBL9996050 | 0.80 | TBXAS1 (0.97) | TBXAS1ALDH1A1KDM4EMAPK1LTA4H | |
| SCHEMBL7555194 | 0.77 | TBXAS1 (0.66) | TBXAS1ALDH1A1KDM4EMAPK1LTA4H | |
| SCHEMBL4901152 | 0.75 | IDO1 (0.44) | TBXAS1ALDH1A1KDM4E | |
| SCHEMBL3581172 | 0.74 | ALDH1A1 (0.85) | TBXAS1ALDH1A1KDM4EMAPK1KMT2A | |
| SCHEMBL12382 | 0.74 | KMT2A (0.87) | TBXAS1ALDH1A1KDM4EKMT2ANOS1 | |
| SCHEMBL1928520 | 0.74 | TBXAS1 (0.68) | TBXAS1ALDH1A1KDM4EKMT2ANOS1 | |
| SCHEMBL9451380 | 0.74 | TBXAS1 (0.68) | TBXAS1ALDH1A1KDM4EKMT2ANOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242656-A1 | N-Substituted-N-Sulfonylaminocyclopropane Compounds and Pharmaceutical Use Thereof | JAPAN TOBACCO INC. | 2008-10-02 | — | — | US | disclosed |
| EP-1694638-A1 | N-SUBSTITUTED-N-SULFONYLAMINOCYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-20050222146-A1 | N-substituted-n-sulfonylaminocyclopropane compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2005-10-06 | — | — | US | disclosed |
| WO-2005058808-A1 | N-SUBSTITUTED-N-SULFONYLAMINOCYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242656-A1 | N-Substituted-N-Sulfonylaminocyclopropane Compounds and Pharmaceutical Use Thereof | MMP13, MMP11, MMP3 | TBXAS1 2667/4885ALDH1A1 425/4885KDM4E 2523/4885 |
| US-20050222146-A1 | N-substituted-n-sulfonylaminocyclopropane compounds and pharmaceutical use thereof | MMP13, MMP11, MMP1 | TBXAS1 2679/4885ALDH1A1 425/4885KDM4E 2481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.