SCHEMBL6294995

SCHEMBL6294995

C[Si](C)(C)C1=CCCCCC1

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
CXCR3 P49682 1/20 0.31
HDAC4 P56524 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
ELANE P08246 1/20 0.30
ALOX15 P16050 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23532425 1.00 KDM1A (0.31) KDM1AALDH1A1CYP3A4CXCR3HDAC4
SCHEMBL6291549 1.00 KDM1A (0.31) KDM1AALDH1A1CYP3A4CXCR3HDAC4
SCHEMBL6291550 1.00 KDM1A (0.31) KDM1AALDH1A1CYP3A4CXCR3HDAC4
SCHEMBL23532623 1.00 KDM1A (0.31) KDM1AALDH1A1CYP3A4CXCR3HDAC4
SCHEMBL1640058 0.97 KDM1A (0.32) KDM1AALDH1A1CYP3A4HDAC4HDAC2
SCHEMBL335949 0.90
SCHEMBL17241764 0.81
SCHEMBL7125955 0.79 KDM1A (0.33) KDM1AHDAC4HDAC2HDAC8HDAC6
SCHEMBL4272346 0.78 KDM1A (0.30) KDM1AALDH1A1CYP3A4
SCHEMBL299770 0.78 KDM1A (0.30) KDM1AALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4413085-A1 SILICON-AND ZINC-CONTAINING COUPLING AGENT FOR CELLULOSIC MATERIAL-POLYMER COMPOSITES Arkema, Inc. (US) 2024-08-14 EP claimed
CN-118318010-A Coupling agents containing silicon and zinc for cellulosic material-polymer composites 阿科玛股份有限公司 2024-07-09 CN claimed
WO-2023059592-A1 SILICON-AND ZINC-CONTAINING COUPLING AGENT FOR CELLULOSIC MATERIAL-POLYMER COMPOSITES ARKEMA INC. (US) 2023-04-13 WO claimed
US-20220056275-A1 SILICON- AND ZINC-CONTAINING COUPLING AGENT FOR CELLULOSIC MATERIAL-POLYMER COMPOSITES ARKEMA INC. 2022-02-24 US claimed
EP-4413085-A1 SILICON-AND ZINC-CONTAINING COUPLING AGENT FOR CELLULOSIC MATERIAL-POLYMER COMPOSITES Arkema, Inc. (US) 2024-08-14 EP disclosed
CN-118318010-A Coupling agents containing silicon and zinc for cellulosic material-polymer composites 阿科玛股份有限公司 2024-07-09 CN disclosed
WO-2023059592-A1 SILICON-AND ZINC-CONTAINING COUPLING AGENT FOR CELLULOSIC MATERIAL-POLYMER COMPOSITES ARKEMA INC. (US) 2023-04-13 WO disclosed
US-20230051031-A1 MULTI-FUNCTIONAL HYBRID MATERIAL BASED ON SEPIOLITE FOR ENVIRONMENTAL RECOVERY AND BIO-REMEDIATION CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 2023-02-16 US disclosed
US-20230034883-A1 MULTI-FUNCTIONAL HYBRID MATERIAL BASED ON NATURAL CLAYS FOR ENVIRONMENTAL RECOVERY AND BIO-REMEDIATION CONSIGLIO NAZIONALE DELLE RICERCHE (60%) (IT) 2023-02-02 US disclosed
EP-4076729-A1 MULTI-FUNCTIONAL HYBRID MATERIAL BASED ON NATURAL CLAYS FOR ENVIRONMENTAL RECOVERY AND BIO-REMEDIATION Consiglio Nazionale Delle Ricerche (IT) 2022-10-26 EP disclosed
EP-4076730-A1 MULTI-FUNCTIONAL HYBRID MATERIAL BASED ON SEPIOLITE FOR ENVIRONMENTAL RECOVERY AND BIO-REMEDIATION Consiglio Nazionale Delle Ricerche (IT) 2022-10-26 EP disclosed
US-20220056275-A1 SILICON- AND ZINC-CONTAINING COUPLING AGENT FOR CELLULOSIC MATERIAL-POLYMER COMPOSITES ARKEMA INC. 2022-02-24 US disclosed
WO-2021124097-A1 MULTI-FUNCTIONAL HYBRID MATERIAL BASED ON SEPIOLITE FOR ENVIRONMENTAL RECOVERY AND BIO-REMEDIATION CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 2021-06-24 WO disclosed
WO-2021124103-A1 MULTI-FUNCTIONAL HYBRID MATERIAL BASED ON NATURAL CLAYS FOR ENVIRONMENTAL RECOVERY AND BIO-REMEDIATION CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 2021-06-24 WO disclosed
US-6951942-B2 Glucocorticoid-selective anti-inflammatory agents ABBOTT LABORATORIES (US) 2005-10-04 US disclosed
US-20030073703-A1 Glucocortiocoid-selective antinflammatory agents ABBOTT LABORATORIES AND LIGAND PHARMACEUTICALS INCORPORATED 2003-04-17 US disclosed
EP-1299392-A2 GLUCOCORTIOCOID-SELECTIVE ANTIINFLAMMATORY AGENTS Abbott Laboratories (US) 2003-04-09 EP disclosed
US-6506766-B1 A pharmaceutical composition for use in treating inflammation, immune, autoimmune, and inflammatory diseases in a mammal by selectively modulating the activation, repression, agonism, and antagonism effects of the mammal's glucocorticoid ABBOTT LABORATORIES 2003-01-14 US disclosed
EP-1053239-B1 GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS ABBOTT LAB (US) 2003-01-08 EP disclosed
WO-2002002565-A2 GLUCOCORTIOCOID-SELECTIVE ANTIINFLAMMATORY AGENTS ABBOTT LABORATORIES (US) 2002-01-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030073703-A1 Glucocortiocoid-selective antinflammatory agents NR3C1, GPR119, MC2R KDM1A 3861/4885ALDH1A1 3187/4885CYP3A4 4325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.