SCHEMBL6295118

SCHEMBL6295118

Nc1ccccc1Nc1cccc(C(c2cccc(Nc3ccccc3N)c2)(C(F)(F)F)C(F)(F)F)c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.77
GAA P10253 4/20 0.77
ALDH1A1 P00352 3/20 0.77
SMN1; SMN2 Q16637 2/20 0.77
RAB9A P51151 1/20 0.77
KDM4E B2RXH2 4/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
LMNA P02545 2/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
GFER P55789 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
TP53 P04637 1/20 0.46
APP P05067 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
SNCA P37840 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4064881 0.87 MAPT (1.00) MAPTGAAALDH1A1SMN1; SMN2RAB9A
SCHEMBL29414647 0.87 MAPT (1.00) MAPTGAAALDH1A1SMN1; SMN2RAB9A
SCHEMBL6290887 0.82 MAPT (0.59) MAPTGAAALDH1A1SMN1; SMN2RAB9A
SCHEMBL29708495 0.79 GAA (0.77) MAPTGAAALDH1A1SMN1; SMN2RAB9A
SCHEMBL376200 0.79 GAA (0.77) MAPTGAAALDH1A1SMN1; SMN2RAB9A
SCHEMBL29540467 0.79 GAA (0.77) MAPTGAAALDH1A1SMN1; SMN2RAB9A
SCHEMBL7166997 0.79 MAPT (0.75) MAPTGAAALDH1A1SMN1; SMN2RAB9A
SCHEMBL28465275 0.77 MAPT (0.76) MAPTGAAALDH1A1SMN1; SMN2RAB9A
SCHEMBL4605709 0.76 MAPK1 (0.59) MAPTGAAALDH1A1SMN1; SMN2RAB9A
SCHEMBL21886435 0.76 MAPT (0.46) MAPTGAAALDH1A1SMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6855774-B2 Crosslinkable elastomer composition DAIKIN INDUSTRIES, LTD. (JP) 2005-02-15 US disclosed
US-20050020748-A1 Molded article of a crosslinked fluorine-containing elastomer containing an inorganic filler; heat resistance for use at high temperature, resistance to high density plasma; use sealing semiconductor manufacturing equipment DAIKIN INDUSTRIES, LTD. (JP) 2005-01-27 US disclosed
EP-1464671-A1 ELASTOMER FORMED PRODUCT Daikin Industries, Ltd. (JP) 2004-10-06 EP disclosed
US-20030191247-A1 Crosslinkable elastomer composition DAIKIN INDUSTRIES, LTD. (JP) 2003-10-09 US disclosed