SCHEMBL6290887

SCHEMBL6290887

Nc1ccccc1Nc1ccc(C(c2ccc(Nc3ccccc3N)cc2)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.59
KDM4E B2RXH2 4/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
TP53 P04637 1/20 0.59
APP P05067 1/20 0.59
HPGD P15428 1/20 0.59
ALOX15 P16050 1/20 0.59
SNCA P37840 1/20 0.59
BLM P54132 1/20 0.59
HSD17B10 Q99714 1/20 0.59
GAA P10253 5/20 0.58
ALDH1A1 P00352 4/20 0.58
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
LMNA P02545 1/20 0.58
CYP1A2 P05177 1/20 0.58
CYP2D6 P10635 1/20 0.58
CYP2C9 P11712 1/20 0.58
CYP2C19 P33261 1/20 0.58
TDP1 Q9NUW8 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6290876 0.91 MAPT (0.54) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL29824523 0.86 MAPT (0.68) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL15875869 0.86 MAPT (0.68) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL6295118 0.82 MAPT (0.77) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL4607773 0.81 MAPT (0.86) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL29708495 0.80 GAA (0.77) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL376200 0.80 GAA (0.77) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL29540467 0.80 GAA (0.77) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL15875871 0.79 MAPT (0.65) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL30323778 0.79 MAPT (0.65) MAPTKDM4ESMN1; SMN2TP53APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6855774-B2 Crosslinkable elastomer composition DAIKIN INDUSTRIES, LTD. (JP) 2005-02-15 US disclosed
US-20050020748-A1 Molded article of a crosslinked fluorine-containing elastomer containing an inorganic filler; heat resistance for use at high temperature, resistance to high density plasma; use sealing semiconductor manufacturing equipment DAIKIN INDUSTRIES, LTD. (JP) 2005-01-27 US disclosed
EP-1464671-A1 ELASTOMER FORMED PRODUCT Daikin Industries, Ltd. (JP) 2004-10-06 EP disclosed
US-20030191247-A1 Crosslinkable elastomer composition DAIKIN INDUSTRIES, LTD. (JP) 2003-10-09 US disclosed