Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UPP1 | Q16831 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | UBE2D3 | P61077 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6291233 | 0.86 | ALDH1A1 (0.47) | UPP1POLBHPGDALDH1A1CHRNB2 | |
| SCHEMBL14364291 | 0.85 | ALDH1A1 (0.47) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL13065489 | 0.85 | ALDH1A1 (0.47) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL3293698 | 0.85 | ALDH1A1 (0.47) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL3293695 | 0.85 | ALDH1A1 (0.47) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL14377586 | 0.85 | ALDH1A1 (0.47) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL3990202 | 0.80 | HPGD (0.49) | UPP1HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL13843285 | 0.80 | HPGD (0.49) | UPP1HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL3990198 | 0.80 | HPGD (0.49) | UPP1HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL14853799 | 0.79 | ALDH1A1 (0.49) | POLBHPGDALDH1A1CHRNB2CHRNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6891036-B2 | Process for the preparation of ribofuranose derivatives | INALCO S.P.A. (IT) | 2005-05-10 | — | — | US | claimed |
| US-20040158059-A1 | Process for the preparation of ribofuranose derivatives | INALCO S.P.A. (IT) | 2004-08-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040158059-A1 | Process for the preparation of ribofuranose derivatives | RNGTT, RPIA, MRM1 | UPP1 61/4885POLB 705/4885HPGD 2092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.