Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.73 |
| ▸ | IL1RN | P18510 | 1/20 | 0.73 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | PKM | P14618 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | CA12 | O43570 | 4/20 | 0.61 |
| ▸ | CA9 | Q16790 | 4/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194421 | 0.92 | KEAP1 (0.73) | KEAP1IL1RNERAP1KMT2AMEN1 | |
| SCHEMBL5037041 | 0.85 | UQCRB (0.66) | KEAP1IL1RNERAP1KMT2AMEN1 | |
| SCHEMBL25031372 | 0.85 | KEAP1 (1.00) | KEAP1IL1RNERAP1KMT2AMEN1 | |
| Phenyl(Phenylsulfonyl)Amine SCHEMBL114765 | 0.85 | KEAP1 (1.00) | KEAP1IL1RNERAP1KMT2AMEN1 | |
| Phenyl(Phenylsulfonyl)Amine SCHEMBL11513007 | 0.83 | KEAP1 (0.95) | KEAP1IL1RNERAP1KMT2AMEN1 | |
| Phenyl(Phenylsulfonyl)Amine SCHEMBL6399560 | 0.83 | KEAP1 (0.95) | KEAP1IL1RNERAP1KMT2AMEN1 | |
| Phenyl(Phenylsulfonyl)Amine SCHEMBL27503772 | 0.83 | KEAP1 (0.95) | KEAP1IL1RNERAP1KMT2AMEN1 | |
| SCHEMBL9001182 | 0.81 | KMT2A (1.00) | KEAP1IL1RNERAP1KMT2AMEN1 | |
| SCHEMBL5342570 | 0.81 | CES1 (0.75) | KMT2AMEN1ALDH1A1CA2CA1 | |
| SCHEMBL482662 | 0.81 | CA12 (0.62) | KMT2AMEN1ALDH1A1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527152-A | Biphenylsulfonamide compound and method for preventing and treating crop pests by using same | 西北农林科技大学 | 2021-10-22 | — | — | CN | claimed |
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-03-14 | — | — | US | claimed |
| US-5879869-A | HAVING LIGHT-INSENSITIVE HYDROPHILIC COLLOID LAYER EXHIBITING ANTIHALATION EFFECT | FUJI PHOTO FILM CO., LTD (JP) | 1999-03-09 | — | — | US | claimed |
| US-4213898-A | FOR POLYACRYLONITRILE | SANDOZ LTD. (CH) | 1980-07-22 | — | — | US | claimed |
| US-4140684-A | FOR POLYESTERS, POLYAMIDES, AND CELLULOSE ACETATES | FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) | 1979-02-20 | — | — | US | claimed |
| CN-113527152-A | Biphenylsulfonamide compound and method for preventing and treating crop pests by using same | 西北农林科技大学 | 2021-10-22 | — | — | CN | disclosed |
| CN-102153481-B | Application of thionyl chloride and alcohol as selective deacylation reagents for N-aryl fatty amide or N-heterocyclic fatty amide | UNIV SOUTHWEST | 2013-09-18 | — | — | CN | disclosed |
| CN-102153481-A | Application of thionyl chloride and alcohol as selective deacylation reagents for N-aryl fatty amide or N-heterocyclic fatty amide | UNIV SOUTHWEST | 2011-08-17 | — | — | CN | disclosed |
| US-6855719-B1 | Imidazo[1,2-A]pyridine and pyrazolo[2,3-A]pyridine derivatives | ASTRAZENECA AB (SE) | 2005-02-15 | — | — | US | disclosed |
| CN-1174981-C | Imidazo [1, 2-A ] pyridine and pyrazolo [2, 3-A ] pyridine derivatives | — | 2004-11-10 | — | — | CN | disclosed |
| EP-1214318-B1 | IMIDAZO[1,2-A]PYRIDINE AND PYRAZOLO[2,3-A]PYRIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2003-10-08 | — | — | EP | disclosed |
| CN-1370163-A | Imidazo [1,2-A] pyridine and pyrazolo [2,3-a] pyridine derivatives | ASTRAZENECA AB (SE) | 2002-09-18 | — | — | CN | disclosed |
| US-4202814-A | AZO DYES GIVING FAST RED COLOR | CIBA-GEIGY CORPORATION (US) | 1980-05-13 | — | — | US | disclosed |
| US-4198205-A | SULFONIC ACID-FREE DISPERSE DYES | BASF AKTIENGESELLSCHAFT (DE) | 1980-04-15 | — | — | US | disclosed |
| US-4179435-A | SULPHONIC ACID-FREE | CIBA-GEIGY CORPORATION (US) | 1979-12-18 | — | — | US | disclosed |
| US-4140684-A | FOR POLYESTERS, POLYAMIDES, AND CELLULOSE ACETATES | FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) | 1979-02-20 | — | — | US | disclosed |
| US-4115381-A | FOR POLYESTER FIBERS | CIBA-GEIGY CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |
| US-4032532-A | AZO DYES | SANDOZ LTD. (CH) | 1977-06-28 | — | — | US | disclosed |
| US-4016151-A | Phenyl-substituted phthalazone azo dyes with a coupling component of the phenol, napthol, acetoacetarylide, pyrazolone, quinolone, pyridine, pyrimidone or isoquinolone series | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |
| US-3998803-A | TEXTILES | FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) | 1976-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | MTTP, CETP, FABP1 | KEAP1 906/4885IL1RN 676/4885ERAP1 438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.