Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PGD | P52209 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CPA1 | P15085 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15698565 | 1.00 | TSHR (0.39) | TSHRPDE4APGDMAPTABCC4 | |
| SCHEMBL27696125 | 1.00 | TSHR (0.39) | TSHRPDE4APGDMAPTABCC4 | |
| SCHEMBL6120459 | 0.98 | TSHR (0.38) | TSHRPDE4APGDMAPTABCC4 | |
| SCHEMBL4539895 | 0.98 | TSHR (0.38) | TSHRPDE4APGDMAPTABCC4 | |
| SCHEMBL27702751 | 0.98 | TSHR (0.38) | TSHRPDE4APGDMAPTABCC4 | |
| SCHEMBL28068419 | 0.87 | MAPT (0.42) | TSHRPDE4APGDMAPTABCC4 | |
| SCHEMBL3892239 | 0.85 | MAPT (0.41) | TSHRPDE4APGDMAPTABCC4 | |
| SCHEMBL4538038 | 0.83 | LMNA (0.41) | TSHRMAPTABCC4CYP3A4NFKB1 | |
| SCHEMBL20819989 | 0.80 | MAPT (0.34) | MAPTABCC4ALDH1A1DDAH1GRIK1 | |
| SCHEMBL22552623 | 0.80 | MAPT (0.34) | MAPTABCC4ALDH1A1DDAH1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1536999-B | Crystalline forms of fluvastatin sodium | CIBA SC HOLDING AG | 2012-08-08 | — | — | CN | claimed |
| WO-2012063115-A2 | PROCESS FOR THE PREPARATION OF ROSUVASTATIN CALCIUM VIA NOVEL AMINE INTERMEDIATE | JUBILANT LIFE SCIENCES LTD. (IN) | 2012-05-18 | — | — | WO | claimed |
| WO-2010030201-A2 | STABLE ORAL PHARMACEUTICAL COMPOSITION CONTAINING A PHARMACEUTICALLY ACCEPTABLE SALT OF [(E)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2- [METHYL(METHYLSULFONYL)AMINO]PYRIMIDINE-5-YL] (3R, 5S) - 3,5 DIHYDROXYHEPT-6- ENOIC ACID | ZAKLADY FARMACEUTYCZNE POLPHARMA SA (PL) | 2010-03-18 | — | — | WO | claimed |
| JP-2007507417-A | — | — | 2007-03-29 | — | — | JP | claimed |
| EP-1667974-A1 | PROCESS FOR PRODUCING HIGH PURITY 3,5-DIHYDROXY-6-HEPTENOIC ACID DERIVATIVE | Nissan Chemical Industries, Ltd. (JP) | 2006-06-14 | — | — | EP | claimed |
| EP-1539698-A1 | METHOD FOR PRODUCING A 3,5-DIHYDROXY-6-HEPTENOATE | Nissan Chemical Industries, Ltd. (JP) | 2005-06-15 | — | — | EP | claimed |
| WO-2005033083-A1 | PROCESS FOR PRODUCING HIGH PURITY 3,5-DIHYDROXY-6-HEPTENOIC ACID DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-04-14 | — | — | WO | claimed |
| CN-1536999-A | Crystalline forms of fluvastatin sodium | �������⻯ѧƷ�ع�����˾ | 2004-10-13 | — | — | CN | claimed |
| WO-2004026838-A1 | METHOD FOR PRODUCING A 3,5-DIHYDROXY-6-HEPTENOATE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-01 | — | — | WO | claimed |
| EP-1339409-A1 | USE OF ROSUVASTATIN (ZD-4522) IN THE TREATMENT OF HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA | AstraZeneca AB (SE) | 2003-09-03 | — | — | EP | claimed |
| EP-1223918-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A HMG COA REDUCTASE INHIBITOR | AstraZeneca AB (SE) | 2002-07-24 | — | — | EP | claimed |
| WO-2002041895-A1 | USE OF ROSUVASTATIN (ZD-4522) IN THE TREATMENT OF HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA | ASTRAZENECA AB (SE) | 2002-05-30 | — | — | WO | claimed |
| WO-2001054668-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A HMG REDUCTASE INHIBITOR | ASTRAZENECA AB (SE) | 2001-08-02 | — | — | WO | claimed |
| EP-0300249-B1 | 7-[1H-pyrrol-3-yl]-substituted 3,5-dihydroxy-heptane acids, their corresponding delta-lactones and salts, processes for their manufacture, their use as medicines, pharmaceutical preparations and intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-03 | — | — | EP | claimed |
| JP-10067744-A | — | — | None | — | — | JP | disclosed |
| US-11466252-B2 | Expansion and differentiation of inner ear supporting cells and methods of use thereof | MASSACHUSETTS EYE AND EAR INFIRMARY (US) | 2022-10-11 | — | — | US | disclosed |
| WO-2021217740-A1 | COMPOSITIONS AND METHODS FOR INHIBITING VIRUS INFECTION | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2021-11-04 | — | — | WO | disclosed |
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |
| US-5055484-A | Anticholesterol and antilipemic agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |
| EP-0252476-A2 | Trans-6-[2-(N-heteroaryl-3,5-disubstituted) pyrazol-4-yl)-ethyl]- or ethenyl] tetrahydro-4-hydroxypyran-2-one-derivatives a process for their preparation and the use thereof | WARNER-LAMBERT COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |