Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PGD | P52209 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3892239 | 0.98 | MAPT (0.41) | MAPTABCC4TSHRALDH1A1USP2 | |
| SCHEMBL15698565 | 0.87 | TSHR (0.39) | MAPTABCC4TSHRALDH1A1USP2 | |
| SCHEMBL629530 | 0.87 | TSHR (0.39) | MAPTABCC4TSHRALDH1A1USP2 | |
| SCHEMBL27696125 | 0.87 | TSHR (0.39) | MAPTABCC4TSHRALDH1A1USP2 | |
| SCHEMBL27702751 | 0.85 | TSHR (0.38) | MAPTABCC4TSHRALDH1A1USP2 | |
| SCHEMBL4539895 | 0.85 | TSHR (0.38) | MAPTABCC4TSHRALDH1A1USP2 | |
| SCHEMBL6120459 | 0.85 | TSHR (0.38) | MAPTABCC4TSHRALDH1A1USP2 | |
| SCHEMBL3979255 | 0.78 | GPR84 (0.48) | MAPTABCC4ALDH1A1USP2CYP3A4 | |
| SCHEMBL5859613 | 0.78 | MAPT (0.48) | MAPTABCC4TSHRALDH1A1USP2 | |
| SCHEMBL463287 | 0.77 | GPR84 (0.47) | MAPTABCC4ALDH1A1USP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105503815-A | Preparation method of synthetic intermediate of Lipitor | UNIV LANZHOU | 2016-04-20 | — | — | CN | disclosed |