Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1468357 | 0.86 | IDO1 (0.58) | IDO1LOXL2TAAR1AGXTDAO | |
| SCHEMBL16561361 | 0.86 | IDO1 (0.58) | IDO1LOXL2TAAR1AGXTDAO | |
| Hydrochloric Acid SCHEMBL7941845 | 0.83 | IDO1 (0.55) | IDO1LOXL2TAAR1AGXTDAO | |
| SCHEMBL27051 | 0.83 | — | — | |
| SCHEMBL3242177 | 0.78 | LMNA (0.63) | ALDH1A1CYP3A4PLA2G1BATG4BLMNA | |
| SCHEMBL10544415 | 0.78 | PTPN5 (0.42) | IDO1LOXL2TAAR1AGXTDAO | |
| SCHEMBL19993270 | 0.78 | MAOB (0.56) | IDO1LOXL2TAAR1AGXTCYP3A4 | |
| SCHEMBL11980113 | 0.76 | CALM1 (0.67) | IDO1LOXL2TAAR1ALDH1A1PLA2G1B | |
| SCHEMBL576416 | 0.76 | CALM1 (0.67) | IDO1LOXL2TAAR1ALDH1A1PLA2G1B | |
| SCHEMBL1718228 | 0.76 | CALM1 (0.67) | IDO1LOXL2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927216-B2 | Cyclic sulfonyl compounds as inhibitors of metalloproteases | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2005-08-09 | — | — | US | disclosed |