SCHEMBL27051

SCHEMBL27051

[CH2]c1ccc(F)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2089655 0.90 BCL2L1 (0.44)
SCHEMBL6295435 0.83 IDO1 (0.46)
SCHEMBL5540625 0.83 HSPB1 (0.48)
SCHEMBL3103454 0.81 KCNN4 (0.37)
SCHEMBL9052212 0.79 LTA4H (0.59)
SCHEMBL147275 0.78
SCHEMBL13499 0.78
SCHEMBL3242177 0.77 LMNA (0.63)
Bromide SCHEMBL6770232 0.74
Fluoride SCHEMBL21816906 0.74 CA1 (0.57)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 14114 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
CN-118344265-A Amide compound and preparation method and application thereof 河北大学 2024-07-16 CN claimed
US-20240218022-A1 ANTI-VISTA MACROCYCLIC PEPTIDES AND COMPOSITIONS BRISTOL-MYERS SQUIBB COMPANY (US) 2024-07-04 US claimed
WO-2024133360-A1 NOVEL CANNABINOID-INSPIRED INHIBITORS OF AUTOTAXIN EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) 2024-06-27 WO claimed
CN-118239883-A Preparation method of lysine-specific demethylase 1 (LSD 1) inhibitor 江苏联环药业股份有限公司 2024-06-25 CN claimed
CN-118206748-A PCB electroplating additive and preparation method thereof 广东利尔化学有限公司 2024-06-18 CN claimed
CN-114773586-B Poly (fluorobenzene ester) polymer material and synthetic method thereof 西安交通大学 2024-06-14 CN claimed
EP-3849664-B1 PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE GENENTECH INC (US) 2024-06-12 EP claimed
CN-118164997-A Sesquiterpene lactone scaberol C thioether derivative, and preparation method and application thereof 沈阳药科大学 2024-06-11 CN claimed
CN-118164998-A Sesquiterpene lactone scaberol C dithio carbamate derivative and preparation method and application thereof 沈阳药科大学 2024-06-11 CN claimed
US-4240823-A New plant growth regulating compositions which contain derivatives of N-acyl methionine PHILAGRO S.A. (FR) 1980-12-23 US claimed
US-4239770-A Substituted 2-pyrrolidinones for counteracting cerebral insufficiency HOFFMANN-LA ROCHE INC. (US) 1980-12-16 US claimed
US-4217355-A N-(I-THIAZOLYL)-A-(SUBSTITUTED AMINO)AMIDES, ANTIINFLAMMATORY, IMMUNOREGULATIVE PFIZER INC. (US) 1980-08-12 US claimed
EP-0010287-A1 Gamma-azolyl compounds, growth regulating compositions, process for producing them and process for regulating the growth of plants BASF Aktiengesellschaft (DE) 1980-04-30 EP claimed
EP-0005014-A1 Clavulanic acid derivatives, preparation and compositions BEECHAM GROUP PLC (GB) 1979-10-31 EP claimed
EP-0001682-A2 Heterocyclic compounds and their use as pesticides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-05-02 EP claimed
US-4107326-A ANTIHYPERTENSIVE AGENTS, DIURETICS AMERICAN CYANAMID COMPANY (US) 1978-08-15 US claimed
US-3979390-A Butyrophenone derivatives and production thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-09-07 US claimed
US-3975386-A PYRIDOPYRIMIDINE-ONE INTERMEDIATES SANDOZ, INC. (US) 1976-08-17 US claimed
US-3931178-A ANTIHISTAMINES SANDOZ INC. (US) 1976-01-06 US claimed