Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 1.00 |
| ▸ | MMP9 | P14780 | 10/20 | 1.00 |
| ▸ | MMP13 | P45452 | 8/20 | 1.00 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.59 |
| ▸ | MMP1 | P03956 | 7/20 | 0.59 |
| ▸ | MMP8 | P22894 | 3/20 | 0.52 |
| ▸ | MMP12 | P39900 | 3/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6296125 | 1.00 | MMP2 (1.00) | MMP2MMP9MMP13ADAM17MMP1 | |
| SCHEMBL6295428 | 0.93 | MMP13 (0.86) | MMP2MMP9MMP13ADAM17MMP1 | |
| SCHEMBL6295430 | 0.93 | MMP13 (0.86) | MMP2MMP9MMP13ADAM17MMP1 | |
| SCHEMBL6291766 | 0.88 | MMP2 (1.00) | MMP2MMP9MMP13ADAM17MMP1 | |
| SCHEMBL6296122 | 0.81 | MMP2 (0.86) | MMP2MMP9MMP13ADAM17MMP1 | |
| SCHEMBL6292546 | 0.79 | MMP2 (1.00) | MMP2MMP9MMP13ADAM17MMP1 | |
| SCHEMBL6292544 | 0.79 | MMP2 (1.00) | MMP2MMP9MMP13ADAM17MMP1 | |
| SCHEMBL6296172 | 0.76 | MMP2 (0.71) | MMP2MMP9MMP13ADAM17MMP1 | |
| SCHEMBL6291742 | 0.76 | ADAM17 (1.00) | MMP2MMP9MMP13ADAM17MMP3 | |
| SCHEMBL6291475 | 0.75 | MMP2 (0.77) | MMP2MMP9MMP13ADAM17MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322627-A1 | CYCLIC SULFONYL COMPOUNDS AS INHIBITORS OF METALLOPROTEASES | Bristol-Myers Squibb Pharma Company (US) | 2003-07-02 | — | — | EP | claimed |
| US-20020086853-A1 | Cyclic sulfonyl compounds as inhibitors of metalloproteases | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-07-04 | — | — | US | claimed |
| WO-2002028846-A1 | CYCLIC SULFONYL COMPOUNDS AS INHIBITORS OF METALLOPROTEASES | DUPONT PHARMACEUTICALS COMPANY (US) | 2002-04-11 | — | — | WO | claimed |
| US-6927216-B2 | Cyclic sulfonyl compounds as inhibitors of metalloproteases | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2005-08-09 | — | — | US | disclosed |
| US-20020086853-A1 | Cyclic sulfonyl compounds as inhibitors of metalloproteases | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020086853-A1 | Cyclic sulfonyl compounds as inhibitors of metalloproteases | DPP7, STS, CTRL | MMP2 11/4885MMP9 6/4885MMP13 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.