Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MYOC | Q99972 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6295781 | 0.78 | MEN1 (0.51) | NPC1MEN1KMT2ACA12CA1 | |
| SCHEMBL6295780 | 0.78 | MEN1 (0.51) | NPC1MEN1KMT2ACA12CA1 | |
| SCHEMBL6296156 | 0.78 | ERCC1 (0.67) | NPC1MEN1KMT2ACA12CA1 | |
| SCHEMBL9354167 | 0.77 | KMT2A (0.63) | NPC1MEN1KMT2AALDH1A1PKM | |
| SCHEMBL6297252 | 0.76 | CNR1 (0.70) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL6302141 | 0.75 | CCR5 (0.55) | NPC1MEN1KMT2ACA12CA1 | |
| SCHEMBL23728129 | 0.72 | NPC1 (0.75) | NPC1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16552433 | 0.72 | CASR (0.67) | NPC1MEN1KMT2AALDH1A1PKM | |
| SCHEMBL15306494 | 0.72 | ALDH1A1 (0.58) | NPC1MEN1KMT2AALDH1A1PKM | |
| SCHEMBL6302140 | 0.72 | CNR1 (0.60) | MEN1KMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875764-B1 | Urea and thiourea compounds useful for treatment of coccidiosis | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-04-05 | — | — | US | disclosed |
| EP-1224165-A1 | NOVEL COMPOUNDS | New Pharma Research Sweden AB (SE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001030749-A1 | NOVEL COMPOUNDS | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2001-05-03 | — | — | WO | disclosed |