Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30417071 | 0.87 | ALDH1A1 (0.76) | LMNAKMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL14978294 | 0.81 | LMNA (0.76) | LMNAKDM4EKMT2ASMN1; SMN2GAA | |
| SCHEMBL2378489 | 0.81 | PKM (0.66) | LMNAKMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL5451782 | 0.81 | GAA (0.90) | LMNAKDM4EKMT2ASMN1; SMN2GAA | |
| SCHEMBL7040997 | 0.79 | LMNA (0.69) | LMNAKDM4EKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4749977 | 0.79 | ATM (0.68) | LMNAKMT2AMAPTALDH1A1CYP2C19 | |
| SCHEMBL14574160 | 0.76 | ALDH1A1 (0.72) | LMNAKMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL5067764 | 0.76 | LMNA (0.59) | LMNAKMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2376571 | 0.76 | MAPT (0.68) | LMNAKDM4EKMT2ASMN1; SMN2GAA | |
| SCHEMBL6323061 | 0.76 | LMNA (0.78) | LMNAKMT2ASMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875764-B1 | Urea and thiourea compounds useful for treatment of coccidiosis | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-04-05 | — | — | US | disclosed |
| EP-1224165-A1 | NOVEL COMPOUNDS | New Pharma Research Sweden AB (SE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001030749-A1 | NOVEL COMPOUNDS | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2001-05-03 | — | — | WO | disclosed |