Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | ERN1 | O75460 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18851403 | 0.89 | NPC1 (0.60) | NPC1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL1187473 | 0.84 | ALDH1A1 (0.65) | ALDH1A1TSHRKDM4ETDP1GAA | |
| SCHEMBL20135971 | 0.84 | ALDH1A1 (0.65) | NPC1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL7401545 | 0.82 | ALDH1A1 (0.69) | NPC1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL31469616 | 0.80 | ALDH1A1 (0.72) | NPC1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL27753912 | 0.80 | ALDH1A1 (0.72) | NPC1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL1570740 | 0.80 | ALDH1A1 (0.72) | NPC1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL11044996 | 0.79 | ALDH1A1 (0.59) | ALDH1A1TSHRKDM4ETDP1GAA | |
| SCHEMBL12835408 | 0.79 | ALDH1A1 (0.59) | NPC1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL24389243 | 0.79 | ALDH1A1 (0.57) | NPC1ALDH1A1TSHRKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329466-A | Certain nor-tropan-8-amine-3-aryl or heteroaryl derivatives | DELALANDE S.A. (FR) | 1982-05-11 | — | — | US | claimed |
| JP-52073864-A | — | — | None | — | — | JP | disclosed |
| JP-52083737-A | — | — | None | — | — | JP | disclosed |
| JP-52083762-A | — | — | None | — | — | JP | disclosed |
| US-12583822-B2 | Benzylamine derivative, preparation method therefor and use thereof | ACADEMY OF MILITARY MEDICAL SCIENCES (CN) | 2026-03-24 | — | — | US | disclosed |
| US-20230303494-A1 | BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | ACADEMY OF MILITARY MEDICAL SCIENCES (CN) | 2023-09-28 | — | — | US | disclosed |
| EP-4198017-A1 | BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Academy of Military Medical Sciences (CN) | 2023-06-21 | — | — | EP | disclosed |
| CN-114075123-B | Benzylamine derivative and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-06-06 | — | — | CN | disclosed |
| CN-114075123-A | Benzylamine derivative and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2022-02-22 | — | — | CN | disclosed |
| WO-2022033303-A1 | BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国人民解放军军事科学院军事医学研究院 | 2022-02-17 | — | — | WO | disclosed |
| EP-2419409-A1 | PROCESS FOR THE PREPARATION OF A BIPHENYL-2-YLCARBAMIC ACID ESTER | Glaxo Group Limited (GB) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010119064-A1 | PROCESS FOR THE PREPARATION OF A BIPHENYL-2-YLCARBAMIC ACID ESTER | GLAXO GROUP LIMITED (GB) | 2010-10-21 | — | — | WO | disclosed |
| WO-2010119064-A1 | PROCESS FOR THE PREPARATION OF A BIPHENYL-2-YLCARBAMIC ACID ESTER | GLAXO GROUP LIMITED (GB) | 2010-10-21 | — | — | WO | disclosed |
| EP-0794184-B1 | 6-METHOXY-1H-BENZOTRIAZOLE-5-CARBOXAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO (JP) | 2001-05-30 | — | — | EP | disclosed |
| US-5932568-A | GASTROINTESTINAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0794184-A1 | 6-METHOXY-1H-BENZOTRIAZOLE-5-CARBOXAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1997-09-10 | — | — | EP | disclosed |
| EP-0353372-B1 | Antischizophrenic-S-N-(1-azabicyclo[2.2.2.]oct-3-yl) benzamides and thiobenzamides | SYNTHELABO (FR) | 1993-02-03 | — | — | EP | disclosed |
| JP-S5283737-A | NOVEL CARBOXYLIC ACID AMIDE DERIVATIVES AND PREPARATION THEREOF | YAMANOUCHI PHARMACEUT CO LTD | 1977-07-12 | — | — | JP | disclosed |
| JP-S5283762-A | NOVEL CARBOXYLIC ACID AMIDE | YAMANOUCHI PHARMACEUT CO LTD | 1977-07-12 | — | — | JP | disclosed |
| JP-S5273864-A | PREPARATION OF NOVEL CARBOXYLIC ACID AMIDE DERIVATIVE | YAMANOUCHI PHARMACEUT CO LTD | 1977-06-21 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303494-A1 | BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | CD274, PDCD1, PDCD1LG2 | NPC1 1827/4885ALDH1A1 110/4885TSHR 3296/4885 |
| US-12583822-B2 | Benzylamine derivative, preparation method therefor and use thereof | CD274, PDCD1, PDCD1LG2 | NPC1 805/4885ALDH1A1 612/4885TSHR 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.