Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16948385 | 0.72 | — | — | |
| SCHEMBL5470718 | 0.72 | — | — | |
| SCHEMBL327787 | 0.69 | RECQL (0.38) | ALPLRECQLALOX15 | |
| SCHEMBL24952237 | 0.69 | — | — | |
| SCHEMBL10341130 | 0.69 | ALOX15 (0.37) | RECQLALOX15 | |
| SCHEMBL21203063 | 0.69 | — | — | |
| SCHEMBL24953247 | 0.69 | — | — | |
| SCHEMBL9491790 | 0.69 | — | — | |
| SCHEMBL17924952 | 0.69 | RECQL (0.34) | RECQLALOX15 | |
| SCHEMBL530755 | 0.69 | RECQL (0.30) | RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263561-B1 | Silylated u.v. stabilizers containing hindered tertiary amines | GREAT LAKES CHEMICAL ITALIA (IT) | 1998-05-13 | — | — | EP | claimed |
| US-4946880-A | SILICIC FUNCTIONAL N-SUBSTITUTED PIPERIDINE, MORPHOLINE OR PYROLIDINE COMPOUNDS | ENICHEM SYNTHESIS S.P.A. (IT) | 1990-08-07 | — | — | US | claimed |
| US-4797451-A | VINYL AROMATIC, HINDERED POLYETHER OR DIENE-OLEFIN POLYMERS MODIFIED WITH HINDERED AMINES | ENIRICERCHE S.P.A. (IT) | 1989-01-10 | — | — | US | claimed |
| EP-0162524-B1 | ORGANIC POLYMER STABILISATION | ENICHEM SYNTHESIS S.p.A. (IT) | 1988-11-02 | — | — | EP | claimed |
| EP-0218298-A2 | Solid polymeric stabilizer compounds and process for their manufacturing | ENIRICERCHE S.p.A. (IT) | 1987-04-15 | — | — | EP | claimed |
| EP-0162524-A2 | Organic polymer stabilisation | ENICHEM SYNTHESIS S.p.A. (IT) | 1985-11-27 | — | — | EP | claimed |
| US-6903117-B2 | Indole derivatives for the treatment of osteoporosis | NIKEM RESEARCH S.R.L. (IT) | 2005-06-07 | — | — | US | disclosed |
| US-20040010012-A1 | Selective inhibitor of the biological activity of human osteoclast cells | SMITHKLINE BEECHAM SPA | 2004-01-15 | — | — | US | disclosed |
| US-20020173659-A1 | Indole derivatives for the treatment of osteoporosis | SMITH KLINE BEECHAM SPA | 2002-11-21 | — | — | US | disclosed |
| US-5981525-A | FOR THERAPY OR PROPHYLAXIS OF OSTEOPOROSIS,TUMOURS, ULCERS, AUTOIMMUNE DISEASES, LIPIDEMIC DISORDERS, HYPERCHOLESTEROLEMIC AND ATHEROSCLEROTIC DISEASES, AIDS ALZHEIMER'S DISEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-09 | — | — | US | disclosed |
| US-5905148-A | Photochromic spirooxazine polysiloxanes | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1999-05-18 | — | — | US | disclosed |
| EP-0914321-A1 | INDOLE DERIVATIVES FOR THE TREATMENT OF OSTEOPOROSIS | Smithkline Beecham S.p.A. (IT) | 1999-05-12 | — | — | EP | disclosed |
| EP-0263561-B1 | Silylated u.v. stabilizers containing hindered tertiary amines | GREAT LAKES CHEMICAL ITALIA (IT) | 1998-05-13 | — | — | EP | disclosed |
| US-4853440-A | ULTRAVIOLET RADIATION SCREENS FOR PROPYLENE | ENIRICERCHE, S.P.A. (IT) | 1989-08-01 | — | — | US | disclosed |
| US-4797451-A | VINYL AROMATIC, HINDERED POLYETHER OR DIENE-OLEFIN POLYMERS MODIFIED WITH HINDERED AMINES | ENIRICERCHE S.P.A. (IT) | 1989-01-10 | — | — | US | disclosed |
| EP-0162524-B1 | ORGANIC POLYMER STABILISATION | ENICHEM SYNTHESIS S.p.A. (IT) | 1988-11-02 | — | — | EP | disclosed |
| EP-0263561-A2 | Silylated u.v. stabilizers containing hindered tertiary amines | GREAT LAKES CHEMICAL ITALIA S.r.l. (IT) | 1988-04-13 | — | — | EP | disclosed |
| US-4684726-A | TO STABILIZE POLYOLEFINS AND POLYDIENES | ENICHEM SINTESI, S.P.A. (IT) | 1987-08-04 | — | — | US | disclosed |
| EP-0218298-A2 | Solid polymeric stabilizer compounds and process for their manufacturing | ENIRICERCHE S.p.A. (IT) | 1987-04-15 | — | — | EP | disclosed |
| EP-0162524-A2 | Organic polymer stabilisation | ENICHEM SYNTHESIS S.p.A. (IT) | 1985-11-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010012-A1 | Selective inhibitor of the biological activity of human osteoclast cells | HRH4, HRH3, CNKSR1 | ALPL 1540/4885RECQL 3503/4885ALOX15 4154/4885 |
| US-20020173659-A1 | Indole derivatives for the treatment of osteoporosis | SOST, GHRHR, EBP | ALPL 587/4885RECQL 2474/4885ALOX15 3171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.