SCHEMBL6297728

SCHEMBL6297728

CC[C@H](C)[C@H](NP(=O)(O)O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.45
CA2 P00918 2/20 0.41
CA1 P00915 1/20 0.41
FPR2 P25090 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ATM Q13315 1/20 0.40
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP3 P08254 1/20 0.38
MME P08473 1/20 0.38
ACE P12821 1/20 0.38
CPA1 P15085 1/20 0.38
ACE2 Q9BYF1 1/20 0.38
ENPEP Q07075 2/20 0.36
MAPK1 P28482 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6297727 1.00 ALDH1A1 (0.52) ALDH1A1L3MBTL1CA2CA1FPR2
SCHEMBL30910287 1.00 ALDH1A1 (0.52) ALDH1A1L3MBTL1CA2CA1FPR2
SCHEMBL2991878 0.78 ALDH1A1 (0.50) ALDH1A1L3MBTL1CA2CA1FPR2
SCHEMBL2991880 0.78 ALDH1A1 (0.50) ALDH1A1L3MBTL1CA2CA1FPR2
SCHEMBL42674 0.77 TP53 (0.38) CA2CA1MMP1MMP2MME
SCHEMBL42677 0.77 TP53 (0.38) CA2CA1MMP1MMP2MME
SCHEMBL23260544 0.74 ALDH1A1 (0.59) ALDH1A1L3MBTL1CA2CA1FPR2
SCHEMBL43381 0.74 ALDH1A1 (0.59) ALDH1A1L3MBTL1CA2CA1FPR2
SCHEMBL43380 0.74 ALDH1A1 (0.59) ALDH1A1L3MBTL1CA2CA1FPR2
SCHEMBL584507 0.74 ALDH1A1 (0.59) ALDH1A1L3MBTL1CA2CA1FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12215123-B2 Cordycepin-based derivatized compound with anti-tumor effect NANJING TECH UNIVERSITY (CN) 2025-02-04 US disclosed
US-20240116976-A1 CORDYCEPIN-BASED DERIVATIZED COMPOUND WITH ANTI-TUMOR EFFECT NANJING TECH UNIVERSITY (CN) 2024-04-11 US disclosed
US-6951927-B2 Proteins with integrin-like activity CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2005-10-04 US disclosed
US-6746853-B1 USED IN THE TREATMENT OF INSULIN RELATED DISORDERS SUCH AS TYPE 1 DIABETES AND TYPE 2 DIABETES XENCOR, INC. 2004-06-08 US disclosed
US-6682923-B1 NON-NATURALLY OCCURRING XYLANASE ACTIVITY (XA) PROTEIN; BLEACHING AGENT COMPRISING AS AN ACTIVE INGREDIENT AN XA PROTEIN IN THE BLEACHING PROCESS OF PULP AND IN THE FOOD AND ANIMAL FEED INDUSTRY XENCOR 2004-01-27 US disclosed
WO-2002038746-A9 NOVEL THERMOSTABLE ALKALIPHILIC XYLANASE XENCOR INC (US) 2003-04-24 WO disclosed
US-20030054440-A1 Novel proteins with integrin-like activity CENTER FOR BLOOD RESEARCH 2003-03-20 US disclosed
US-6514729-B1 A non-naturally occurring protein with amino acid substitutions; Exhibits biological activity of human protein; Antiviral agent XENCOR, INC. 2003-02-04 US disclosed
WO-2000068396-A9 BACILLUS CIRCULANS XYLANASE MUTANTS XENCOR INC (US) 2002-07-04 WO disclosed
WO-2002038746-A2 NOVEL THERMOSTABLE ALKALIPHILIC XYLANASE XENCOR (US) 2002-05-16 WO disclosed
WO-2000068387-A9 NUCLEIC ACIDS AND PROTEINS WITH INTERFERON-BETA ACTIVITY XENCOR INC (US) 2002-04-18 WO disclosed
EP-1183359-A2 NUCLEIC ACIDS AND PROTEINS WITH INTERFERON-BETA ACTIVITY Xencor Inc. (US) 2002-03-06 EP disclosed
EP-1179075-A2 BACILLUS CIRCULANS XYLANASE MUTANTS Xencor, Inc. (US) 2002-02-13 EP disclosed
WO-2002004521-A2 PROTEINS WITH INTEGRIN-LIKE ACTIVITY CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2002-01-17 WO disclosed
WO-2000069901-A2 PROTEINS WITH INSULIN-LIKE ACTIVITY USEFUL IN THE TREATMENT OF DIABETES XENCOR, INC. (US) 2000-11-23 WO disclosed
WO-2000068387-A2 NUCLEIC ACIDS AND PROTEINS WITH INTERFERON-BETA ACTIVITY XENCOR, INC. (US) 2000-11-16 WO disclosed
WO-2000068396-A2 BACILLUS CIRCULANS XYLANASE MUTANTS XENCOR, INC. (US) 2000-11-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12215123-B2 Cordycepin-based derivatized compound with anti-tumor effect RNASE1, MCL1, DCK ALDH1A1 2406/4885L3MBTL1 2654/4885CA2 3072/4885
US-20240116976-A1 CORDYCEPIN-BASED DERIVATIZED COMPOUND WITH ANTI-TUMOR EFFECT RNASE1, MCL1, DCK ALDH1A1 2406/4885L3MBTL1 2654/4885CA2 3072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.