Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6297970 | 1.00 | PTGS2 (0.40) | PTGS2ESR1CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL6304314 | 0.90 | ESR1 (0.41) | PTGS2ESR1ALDH1A1CYP19A1CYP11B2 | |
| SCHEMBL6304315 | 0.90 | ESR1 (0.41) | PTGS2ESR1ALDH1A1CYP19A1CYP11B2 | |
| SCHEMBL4599993 | 0.78 | CYP19A1 (0.48) | PTGS2ESR1CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL6300151 | 0.75 | CYP3A4 (0.38) | PTGS2ESR1CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL6297766 | 0.75 | C1S (0.42) | PTGS2ALDH1A1CYP19A1CYP11B2NFKB1 | |
| SCHEMBL6297768 | 0.75 | C1S (0.42) | PTGS2ALDH1A1CYP19A1CYP11B2NFKB1 | |
| SCHEMBL6300153 | 0.75 | CYP3A4 (0.38) | PTGS2ESR1CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL6517636 | 0.74 | ESR1 (0.59) | PTGS2ESR1ALDH1A1CYP19A1CYP11B2 | |
| SCHEMBL987335 | 0.74 | ESR1 (0.64) | PTGS2ESR1NPSR1CYP19A1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875895-B2 | Such as 1,4-bis(2-(4-bromophenyl)-2-phenylethenyl)-2-(2-ethylhexyloxy)-5 -methoxybenzene; for polymerization into a light-emitting material | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-04-05 | — | — | US | disclosed |
| US-20030100786-A1 | Bis (diphenylvinyl) arene compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-05-29 | — | — | US | disclosed |
| EP-1288184-A1 | Bis(diphenylvinyl)arene compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-03-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100786-A1 | Bis (diphenylvinyl) arene compound | CBR1, AR, CYP1B1 | PTGS2 1590/4885ESR1 343/4885CYP1A2 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.