SCHEMBL6298481

SCHEMBL6298481

ClCCCc1ccc(Oc2ccc(CCCCl)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 3/20 0.42
ST14 Q9Y5Y6 1/20 0.41
CALM1 P0DP23 1/20 0.41
PPARG P37231 1/20 0.41
LTA4H P09960 3/20 0.40
EPHX2 P34913 1/20 0.40
IGF1R P08069 1/20 0.40
ALOX15 P16050 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
HRH3 Q9Y5N1 2/20 0.38
PLAAT3 P53816 1/20 0.38
PLAAT5 Q96KN8 1/20 0.38
PLAAT2 Q9NWW9 1/20 0.38
PLAAT4 Q9UL19 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5579005 0.92 FFAR1 (0.55) FFAR1PPARGLTA4HEPHX2FFAR4
SCHEMBL6029750 0.85 FFAR1 (0.45) FFAR1ST14LTA4HEPHX2FFAR4
SCHEMBL28709923 0.84 MAOB (0.40) IGF1RALOX15
SCHEMBL12401880 0.84 LTA4H (0.43) FFAR1CALM1LTA4HEPHX2HRH3
SCHEMBL1796734 0.82 CALM1 (0.62) CALM1IGF1RALOX15
Methylamine SCHEMBL9740790 0.79 TAAR1 (0.59) CALM1IGF1RALOX15
SCHEMBL8497351 0.77 FFAR1 (0.58) FFAR1PPARGLTA4HEPHX2FFAR4
SCHEMBL9190069 0.77 CA1 (0.39) IGF1RALOX15
SCHEMBL9553378 0.77 MAOB (0.43) HRH3
SCHEMBL9502103 0.77 LTA4H (0.44) LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146879-A Photoresist cleaning agent for LED and production process thereof 福建省佑达环保材料有限公司 2024-06-07 CN claimed
CN-118561724-A Preparation method of alkyl-alkyl sulfone compound based on metal reducing agent 西安交通大学 2024-08-30 CN disclosed
US-6942966-B1 libraries formed by permutations; combinatorial chemistry; drug screening ISIS PHARMACEUTICALS, INC. (US) 2005-09-13 US disclosed
US-6559303-B1 Bridgehead atoms are bonded to one or more bridges that interconnect one or more ring systems thereby forming a large cyclic structure. Located in each bridge are two or more nitrogenous moieties that are derivatized with chemical ISIS PHARMACEUTICALS, INC. 2003-05-06 US disclosed
US-6329523-B1 FOR ANTIBACTERIAL PHARMACEUTICAL USE, USEFUL FOR IDENTIFYING METAL CHELATING SPECIES FOR ?HEAVY METAL? THERAPY; IMAGING AGENTS ISIS PHARMACEUTICALS, INC. 2001-12-11 US disclosed
US-6207826-B1 Macrocyclic compounds having nitrogen-containing linkages ISIS PHARMACEUTICALS, INC. 2001-03-27 US disclosed
US-6197965-B1 POLYARYLALKYLAMINO-SUBSTITUED PYRIDINE DERIVATIVES; DRUGS, MEDICINE, DIAGNOSTICS ISIS PHARMACEUTICALS, INC. 2001-03-06 US disclosed
EP-0817787-A4 NITROGENOUS MACROCYCLIC COMPOUNDS ISIS PHARMACEUTICALS INC (US) 2000-09-13 EP disclosed
WO-1998010286-A1 METHODS FOR PROCESSING CHEMICAL COMPOUNDS HAVING REACTIVE FUNCTIONAL GROUPS ISIS PHARMACEUTICALS, INC. (US) 1998-03-12 WO disclosed
EP-0817787-A1 NITROGENOUS MACROCYCLIC COMPOUNDS ISIS PHARMACEUTICALS, INC. (US) 1998-01-14 EP disclosed
WO-1996030377-A1 NITROGENOUS MACROCYCLIC COMPOUNDS ISIS PHARMACEUTICALS, INC. (US) 1996-10-03 WO disclosed