Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28228650 | 0.87 | AKR1C3 (0.53) | NR4A1MAPK1HPGDKMT2AMEN1 | |
| SCHEMBL6299251 | 0.85 | NR4A1 (0.72) | NR4A1SRD5A2MAPK1KMT2AMEN1 | |
| SCHEMBL11231533 | 0.82 | NR4A1 (0.54) | NR4A1SRD5A2MAPK1HPGDKMT2A | |
| SCHEMBL5285030 | 0.82 | ALDH1A1 (0.52) | NR4A1MAPK1POLBCES2CES1 | |
| SCHEMBL7585613 | 0.80 | NR4A1 (0.56) | NR4A1SRD5A2MAPK1HPGDKMT2A | |
| SCHEMBL21835148 | 0.80 | ALDH1A1 (0.53) | NR4A1SRD5A2MAPK1HPGDKMT2A | |
| SCHEMBL3444656 | 0.80 | NR4A1 (0.84) | NR4A1SRD5A2MAPK1KMT2AMEN1 | |
| SCHEMBL9474984 | 0.79 | NR4A1 (0.63) | NR4A1SRD5A2MAPK1KMT2AMEN1 | |
| SCHEMBL7487348 | 0.78 | KMT2A (0.46) | KMT2ARAB9ATDP1 | |
| SCHEMBL9712444 | 0.77 | NR4A1 (0.53) | NR4A1SRD5A2MAPK1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017580-A | Memory enhancing-R-N-(1-azabicyclo[2.2.2.]oct-3-yl)benzamides and thiobenzamides | A.H. ROBINS COMPANY, INCORPORATED A VA CORPORATION | 1991-05-21 | — | — | US | disclosed |