SCHEMBL78316

SCHEMBL78316

O=C(Cl)c1ccccc1C(=O)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.68
GAA P10253 2/20 0.57
MAPT P10636 1/20 0.57
NR4A1 P22736 1/20 0.57
ALDH1A1 P00352 5/20 0.56
ATM Q13315 3/20 0.53
CDC25B P30305 2/20 0.53
ALOX15 P16050 1/20 0.50
CDC25A P30304 1/20 0.48
HSD17B10 Q99714 1/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
SRD5A2 P31213 1/20 0.48
NPSR1 Q6W5P4 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HSP90AA1 P07900 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31672209 1.00 AKR1C3 (0.68) AKR1C3GAAMAPTNR4A1ALDH1A1
SCHEMBL700595 0.88 AKR1C3 (0.85) AKR1C3GAAMAPTNR4A1ALDH1A1
SCHEMBL29447165 0.88 AKR1C3 (0.85) AKR1C3GAAMAPTNR4A1ALDH1A1
SCHEMBL28883310 0.85 AKR1C3 (0.81) AKR1C3GAAMAPTNR4A1ALDH1A1
Fluoride SCHEMBL28319246 0.85 AKR1C3 (0.81) AKR1C3GAAMAPTNR4A1ALDH1A1
SCHEMBL9375700 0.85 ALDH1A1 (0.58) AKR1C3GAAMAPTNR4A1ALDH1A1
SCHEMBL6299251 0.85 NR4A1 (0.72) AKR1C3MAPTNR4A1ALDH1A1ATM
SCHEMBL7590892 0.84 ALDH1A1 (0.54) AKR1C3GAAMAPTNR4A1ALDH1A1
SCHEMBL9712432 0.84 AKR1C3 (0.70) AKR1C3MAPTNR4A1ALDH1A1ATM
SCHEMBL7144396 0.84 AKR1C3 (0.70) AKR1C3GAAMAPTNR4A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105315387-A Modified benzophenone photo-initiator and preparation method thereof ANHUI WANKE NEW TECHNOLOGICAL DEV CO LTD 2016-02-10 CN claimed
US-8128688-B2 Carbon coating on an implantable device ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2012-03-06 US claimed
WO-2008002632-A2 CARBON COATING ON AN IMPLANTABLE DEVICE ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2008-01-03 WO claimed
US-20070298354-A1 Carbon coating on an implantable device ABBOTT CARDIOVASCULAR SYSTEMS INC. 2007-12-27 US claimed
EP-0377191-B1 Radiation-sensitive ethylenically unsaturated copolymerisable compounds, and process for their preparation BASF AG (DE) 1994-03-23 EP claimed
WO-1993014055-A1 PREPARATION OF 2,5-DICHLOROBENZOPHENONES MAXDEM INCORPORATED (US) 1993-07-22 WO claimed
US-5210313-A Friedel crafts aryloylation of 1,4-dichlorobenzene and Lewis acids MAXDEM INCORPORATED (US) 1993-05-11 US claimed
EP-0499836-A2 Carbonate and carbonyl-containing compounds, their preparation and applications BASF Aktiengesellschaft (DE) 1992-08-26 EP claimed
EP-0377191-A2 Radiation-sensitive ethylenically unsaturated copolymerisable compounds, and process for their preparation BASF Aktiengesellschaft (DE) 1990-07-11 EP claimed
US-4312811-A DEHYDROCHLORINATION OF ORTHO-BENZOYLBENZOIC ACID CHLORIDE INTEROX (SOCIETE ANONYME) (BE) 1982-01-26 US claimed
CN-111837075-A Negative ultra-thick film photoresist 默克专利股份有限公司 2020-10-27 CN disclosed
US-10252291-B2 Photo-curing of thermoplastic coatings COLOPLAST A/S (DK) 2019-04-09 US disclosed
CN-108164414-A The synthetic method of high-purity 2- (benzoyl) chlorobenzoyl chloride 江苏佳麦化工有限公司 2018-06-15 CN disclosed
EP-2394676-B1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITIATOR-CONTAINING SCAFFOLDS COLOPLAST AS (DK) 2018-03-28 EP disclosed
US-9629945-B2 Stilbene-based reactive compounds, polymeric matrices formed therefrom, and articles visualizable by fluorescence SURMODICS, INC. (US) 2017-04-25 US disclosed
EP-0425134-A1 Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1991-05-02 EP disclosed
US-4312811-A DEHYDROCHLORINATION OF ORTHO-BENZOYLBENZOIC ACID CHLORIDE INTEROX (SOCIETE ANONYME) (BE) 1982-01-26 US disclosed
US-4312811-A DEHYDROCHLORINATION OF ORTHO-BENZOYLBENZOIC ACID CHLORIDE INTEROX (SOCIETE ANONYME) (BE) 1982-01-26 US disclosed
US-4180674-A ONE STEP ESTERIFICATION OF TRICHLOROMETHYL BENZOPHENONES STAUFFER CHEMICAL COMPANY (US) 1979-12-25 US disclosed
US-3927018-A 3-(2-Methyl-1-imidazolyl)-3-phenyl-1-(3H)isobenzofuranones SANDOZ AG 1975-12-16 US disclosed