Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547693 | 1.00 | NPSR1 (0.55) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL28575888 | 0.94 | NPSR1 (0.57) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL17131834 | 0.94 | NPSR1 (0.61) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL629972 | 0.94 | NPSR1 (0.61) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL6673813 | 0.92 | NPSR1 (0.63) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL10596450 | 0.87 | NPSR1 (0.53) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL1769746 | 0.87 | NPSR1 (0.53) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL8854160 | 0.86 | RAB9A (0.61) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL18240156 | 0.85 | NPC1 (0.54) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL18240146 | 0.85 | NPC1 (0.54) | NPSR1ALDH1A1NPC1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4728051-A1 | STANDARDISING PLURIPOTENT STEM CELLS | United Kingdom Research and Innovation (GB) | 2026-04-22 | — | — | EP | claimed |
| US-20250144056-A1 | ANTIMICROBIAL HOST DEFENSE PEPTIDE-INDUCING COMPOSITIONS AND METHODS OF PRODUCTION AND USE THEREOF | BOARD OF REGENTS FOR THE OKLAHOMA AGRICULTURAL AND MECH COLLEGES (US) | 2025-05-08 | — | — | US | claimed |
| WO-2025059442-A1 | MODULATING PLANT RESPONSES TO STRESS AND GROWTH WITH CHEMICALS | REMOTE EPIGENETICS INC. (US) | 2025-03-20 | — | — | WO | claimed |
| WO-2024256607-A1 | STANDARDISING PLURIPOTENT STEM CELLS | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2024-12-19 | — | — | WO | claimed |
| US-20240398814-A1 | KRAS INHIBITOR AND HDAC INHIBITOR COMBINATION FOR THE TREATMENT OF CANCER | NORTHWESTERN UNIVERSITY | 2024-12-05 | — | — | US | claimed |
| EP-4410284-A1 | COMPOUND AND METHOD FOR THE TREATMENT OF ZELLWEGER SPECTRUM DISORDER | Apteeus (FR) | 2024-08-07 | — | — | EP | claimed |
| US-20230265432-A1 | METHODS AND COMPOSITIONS FOR TREATING ACUTE MYELOID LEUKEMIA | Sanford Burnham Prebys Medical Discovery Institute | 2023-08-24 | — | — | US | claimed |
| WO-2023147573-A2 | ANTIMICROBIAL HOST DEFENSE PEPTIDE-INDUCING COMPOSITIONS AND METHODS OF PRODUCTION AND USE THEREOF | BOARD OF REGENTS FOR THE OKLAHOMA AGRICULTURAL AND MECHANICAL COLLEGES (US) | 2023-08-03 | — | — | WO | claimed |
| EP-3071040-B2 | METHOD FOR SCALABLE SKELETAL MUSCLE LINEAGE SPECIFICATION AND CULTIVATION | UNIV MISSOURI (US) | 2022-12-28 | — | — | EP | claimed |
| EP-3390653-B1 | IMPROVED RECOMBINANT PRODUCTION METHOD | HOFFMANN LA ROCHE (CH) | 2022-08-10 | — | — | EP | claimed |
| US-20200399670-A1 | RECOMBINANT PRODUCTION METHOD | HOFFMANN-LA ROCHE INC. (US) | 2020-12-24 | — | — | US | claimed |
| US-10745731-B2 | Recombinant production method | HOFFMANN-LA ROCHE INC. (US) | 2020-08-18 | — | — | US | claimed |
| US-20190002947-A1 | RECOMBINANT PRODUCTION METHOD | HOFFMANN-LA ROCHE INC. (US) | 2019-01-03 | — | — | US | claimed |
| EP-3390653-A1 | IMPROVED RECOMBINANT PRODUCTION METHOD | H. Hoffnabb-La Roche Ag (CH) | 2018-10-24 | — | — | EP | claimed |
| WO-2017102908-A1 | IMPROVED RECOMBINANT PRODUCTION METHOD | F. HOFFMANN-LA ROCHE AG (CH) | 2017-06-22 | — | — | WO | claimed |
| EP-3071040-A1 | METHOD FOR SCALABLE SKELETAL MUSCLE LINEAGE SPECIFICATION AND CULTIVATION | The Curators of the University of Missouri (US) | 2016-09-28 | — | — | EP | claimed |
| US-20160251625-A1 | METHOD FOR SCALABLE SKELETAL MUSCLE LINEAGE SPECIFICATION AND CULTIVATION | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2016-09-01 | — | — | US | claimed |
| US-20160227830-A1 | METHOD FOR SCALABLE SKELETAL MUSCLE LINEAGE SPECIFICATION AND CULTIVATION | UPSIDE FOODS, INC. | 2016-08-11 | — | — | US | claimed |
| WO-2015066377-A1 | METHOD FOR SCALABLE SKELETAL MUSCLE LINEAGE SPECIFICATION AND CULTIVATION | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2015-05-07 | — | — | WO | claimed |
| WO-2014172776-A1 | COMPOUNDS FOR THE TREATMENT OF MUCOPOLYSACCHARIDOSES | THE HOSPITAL FOR SICK CHILDREN (CA) | 2014-10-30 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10745731-B2 | Recombinant production method | HDAC8, HDAC7, HDAC11 | NPSR1 2976/4885ALDH1A1 4100/4885NPC1 4422/4885 |
| US-20200399670-A1 | RECOMBINANT PRODUCTION METHOD | HDAC8, HDAC7, HDAC11 | NPSR1 2976/4885ALDH1A1 4100/4885NPC1 4422/4885 |
| US-20240398814-A1 | KRAS INHIBITOR AND HDAC INHIBITOR COMBINATION FOR THE TREATMENT OF CANCER | KRAS, HRAS, HDAC1 | NPSR1 4781/4885ALDH1A1 1530/4885NPC1 2902/4885 |
| US-20190002947-A1 | RECOMBINANT PRODUCTION METHOD | HDAC8, HDAC7, HDAC11 | NPSR1 2976/4885ALDH1A1 4100/4885NPC1 4422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.