Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10596450 | 1.00 | NPSR1 (0.53) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL4138868 | 0.98 | NPSR1 (0.55) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL629972 | 0.92 | NPSR1 (0.61) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL17131834 | 0.92 | NPSR1 (0.61) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL6673813 | 0.90 | NPSR1 (0.63) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL3350100 | 0.89 | ALDH1A1 (0.57) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL629973 | 0.87 | NPSR1 (0.55) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL547693 | 0.87 | NPSR1 (0.55) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL3242812 | 0.86 | ALDH1A1 (0.40) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL16369620 | 0.86 | ALDH1A1 (0.40) | NPSR1ALDH1A1NPC1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061545-A1 | HPLC METHOD FOR ANALYZING VORINOSTAT | GENERICS [UK] LIMITED (GB) | 2011-05-26 | — | — | WO | claimed |
| EP-1260529-A1 | Propylene polymers with improved properties | Borealis Technology OY (FI) | 2002-11-27 | — | — | EP | disclosed |