SCHEMBL6300074

SCHEMBL6300074

CC(=O)N(Cl)[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.53
ESR1 P03372 3/20 0.46
ESR2 Q92731 3/20 0.46
FOLH1 Q04609 1/20 0.41
TAAR1 Q96RJ0 3/20 0.41
SLC6A2 P23975 1/20 0.41
ADAMTS5 Q9UNA0 1/20 0.39
POLB P06746 1/20 0.39
CA2 P00918 1/20 0.39
CAMK2A Q9UQM7 1/20 0.39
MME P08473 1/20 0.39
ACE P12821 1/20 0.39
NAALAD2 Q9Y3Q0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29773601 1.00 SLC7A5 (0.53) SLC7A5ESR1ESR2FOLH1TAAR1
SCHEMBL6300076 1.00 SLC7A5 (0.53) SLC7A5ESR1ESR2FOLH1TAAR1
SCHEMBL11710892 0.87 ADAMTS5 (0.50) SLC7A5FOLH1ADAMTS5POLB
SCHEMBL31114841 0.87 ADAMTS5 (0.50) SLC7A5FOLH1ADAMTS5POLB
SCHEMBL7163410 0.85 SLC7A5 (0.58) SLC7A5ESR1ESR2FOLH1TAAR1
SCHEMBL7163413 0.85 SLC7A5 (0.58) SLC7A5ESR1ESR2FOLH1TAAR1
SCHEMBL607090 0.83 SLC7A5 (0.55) SLC7A5ESR1ESR2FOLH1TAAR1
SCHEMBL607091 0.83 SLC7A5 (0.55) SLC7A5ESR1ESR2FOLH1TAAR1
SCHEMBL7373699 0.82 SLC7A5 (0.54) SLC7A5ESR1ESR2FOLH1TAAR1
SCHEMBL31127604 0.82 SLC7A5 (0.54) SLC7A5ESR1ESR2FOLH1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4722228-A1 NEW COMPOUND TARGETING MUSK AND USE THEREOF The University of Tokyo (JP) 2026-04-08 EP disclosed
WO-2024248042-A1 NEW COMPOUND TARGETING MUSK AND USE THEREOF 国立大学法人 東京大学 2024-12-05 WO disclosed
US-11952434-B2 Immunomodulators BRISTOL-MYERS SQUIBB COMPANY (US) 2024-04-09 US disclosed
US-20230312651-A1 Cyclic Peptide, Peptide Complex, and Drug Composition Containing Said Cyclic Peptide and/or Said Peptide Complex THE UNIVERSITY OF TOKYO (JP) 2023-10-05 US disclosed
EP-4180446-A1 CYCLIC PEPTIDE, PEPTIDE COMPLEX, AND DRUG COMPOSITION CONTAINING SAID CYCLIC PEPTIDE AND/OR SAID PEPTIDE COMPLEX The University of Tokyo (JP) 2023-05-17 EP disclosed
US-20230101323-A1 IMMUNOMODULATORS BRISTOL-MYERS SQUIBB COMPANY (US) 2023-03-30 US disclosed
WO-2022232567-A2 CYCLIC PEPTIDE INHIBITORS OF USP22 THE JOHNS HOPKINS UNIVERSITY (US) 2022-11-03 WO disclosed
US-20220275534-A1 Peptide Library Production Method THE UNIVERSITY OF TOKYO (JP) 2022-09-01 US disclosed
CN-107428804-B Immunomodulator 百时美施贵宝公司 2022-06-28 CN disclosed
CN-114652813-A Macrocyclic peptides as immunomodulators 百时美施贵宝公司 2022-06-24 CN disclosed
US-11358988-B2 Immunomodulators BRISTOL-MYERS SQUIBB COMPANY (US) 2022-06-14 US disclosed
CN-107108698-B Macrocyclic peptides as immunomodulators 百时美施贵宝公司 2022-04-29 CN disclosed
EP-3271373-B1 IMMUNOMODULATORS BRISTOL MYERS SQUIBB CO (US) 2022-03-16 EP disclosed
US-6939716-B2 Method for detecting conditions indicative of sepsis WASHINGTON UNIVERSITY (US) 2005-09-06 US disclosed
EP-1427845-A2 METHOD FOR DETECTING SEPSIS Washington University (US) 2004-06-16 EP disclosed
US-20030100122-A1 Method for detecting conditions indicative of sepsis WASHINGTON UNIVERSITY 2003-05-29 US disclosed
WO-2003025212-A2 METHOD FOR DETECTING SEPSIS WASHINGTON UNIVERSITY (US) 2003-03-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11952434-B2 Immunomodulators CD74, ICOS, HAVCR2 SLC7A5 3876/4885ESR1 4130/4885ESR2 2136/4885
US-20230312651-A1 Cyclic Peptide, Peptide Complex, and Drug Composition Containing Said Cyclic Peptide and/or Said Peptide Complex NPPA, NGLY1, NPR1 SLC7A5 609/4885ESR1 2608/4885ESR2 2869/4885
US-20230101323-A1 IMMUNOMODULATORS CD74, ICOS, HAVCR2 SLC7A5 3876/4885ESR1 4130/4885ESR2 2136/4885
US-11358988-B2 Immunomodulators CD74, ICOS, HAVCR2 SLC7A5 3876/4885ESR1 4130/4885ESR2 2136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.