Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | CES1 | P23141 | 4/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31429799 | 1.00 | FOLH1 (0.41) | FOLH1CES2CES1HAO1MAPK1 | |
| SCHEMBL20855304 | 1.00 | FOLH1 (0.41) | FOLH1CES2CES1HAO1MAPK1 | |
| SCHEMBL723055 | 0.98 | FOLH1 (0.42) | FOLH1CES2CES1HAO1MAPK1 | |
| SCHEMBL720525 | 0.91 | FOLH1 (0.44) | FOLH1CES2CES1HAO1MAPK1 | |
| SCHEMBL9936985 | 0.86 | TSHR (0.52) | FOLH1CES2CES1HAO1MAPK1 | |
| SCHEMBL17323034 | 0.81 | TSHR (0.60) | FOLH1OR51E2TSHRLMNANFKB1 | |
| SCHEMBL4003102 | 0.81 | TSHR (0.60) | FOLH1OR51E2TSHRLMNANFKB1 | |
| SCHEMBL8064431 | 0.81 | TSHR (0.60) | FOLH1OR51E2TSHRLMNANFKB1 | |
| SCHEMBL20378734 | 0.81 | TSHR (0.60) | FOLH1OR51E2TSHRLMNANFKB1 | |
| SCHEMBL849456 | 0.81 | TSHR (0.60) | FOLH1OR51E2TSHRLMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6977297-B1 | Methods and means for modification of glucosinolates in plants | PLANT BIOSCIENCE LIMITED (GB) | 2005-12-20 | — | — | US | disclosed |
| EP-1032691-A1 | METHODS AND MEANS FOR MODIFICATION OF GLUCOSINOLATES IN PLANTS | Plant Bioscience Limited (GB) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999027120-A1 | METHODS AND MEANS FOR MODIFICATION OF GLUCOSINOLATES IN PLANTS | PLANT BIOSCIENCE LIMITED (GB) | 1999-06-03 | — | — | WO | disclosed |