Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 6/20 | 0.35 |
| ▸ | CES1 | P23141 | 5/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | BHMT | Q93088 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL722984 | 0.92 | TSHR (0.59) | TSHRGMNNTP53POLBMAPT | |
| SCHEMBL723055 | 0.88 | FOLH1 (0.42) | TSHRFOLH1CES2CES1HAO1 | |
| SCHEMBL722430 | 0.86 | TSHR (0.68) | TSHRGMNNTP53POLBMAPT | |
| SCHEMBL20855304 | 0.86 | FOLH1 (0.41) | TSHRHSD17B10FOLH1CES2CES1 | |
| SCHEMBL31429799 | 0.86 | FOLH1 (0.41) | TSHRHSD17B10FOLH1CES2CES1 | |
| SCHEMBL6300371 | 0.86 | FOLH1 (0.41) | TSHRHSD17B10FOLH1CES2CES1 | |
| SCHEMBL9936987 | 0.82 | TSHR (0.44) | TSHRGMNNTP53POLBMAPT | |
| SCHEMBL720525 | 0.82 | FOLH1 (0.44) | TSHRFOLH1CES2CES1HAO1 | |
| SCHEMBL2452970 | 0.79 | CES2 (0.44) | TSHRGMNNTP53POLBMAPT | |
| SCHEMBL722524 | 0.78 | TSHR (0.54) | TSHRGMNNTP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081712-A1 | PROCESS FOR THE PREPARATION OF HYDROXYCARBOXYLIC ACID COMPOUND OR SALT THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-21 | — | — | WO | disclosed |