Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 5/20 | 0.39 |
| ▸ | CES1 | P23141 | 5/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20855304 | 0.98 | FOLH1 (0.41) | FOLH1MAPK1SLC13A3EGLN1OR51E2 | |
| SCHEMBL31429799 | 0.98 | FOLH1 (0.41) | FOLH1MAPK1SLC13A3EGLN1OR51E2 | |
| SCHEMBL6300371 | 0.98 | FOLH1 (0.41) | FOLH1MAPK1SLC13A3EGLN1OR51E2 | |
| SCHEMBL720525 | 0.93 | FOLH1 (0.44) | FOLH1MAPK1SLC13A3EGLN1OR51E2 | |
| SCHEMBL9936985 | 0.88 | TSHR (0.52) | FOLH1MAPK1SLC13A3EGLN1OR51E2 | |
| SCHEMBL126896 | 0.82 | — | — | |
| SCHEMBL14777048 | 0.80 | OR51E2 (0.43) | FOLH1MAPK1SLC13A3EGLN1OR51E2 | |
| SCHEMBL14776551 | 0.80 | OR51E2 (0.43) | FOLH1MAPK1SLC13A3EGLN1OR51E2 | |
| SCHEMBL2554930 | 0.80 | — | — | |
| SCHEMBL17323034 | 0.78 | TSHR (0.60) | FOLH1OR51E2ALDH1A1LMNAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257630-B1 | BIOSYNTHETIC ENGINEERING OF GLUCOSINOLATES | UNIV COPENHAGEN (DK) | 2016-09-28 | — | — | EP | disclosed |
| US-9096863-B2 | Biosynthetic engineering of glucosinolates | University of Denmark (DK) | 2015-08-04 | — | — | US | disclosed |
| EP-2550251-B1 | PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACID OR SALT THEREOF | SUMITOMO CHEMICAL CO (JP) | 2015-04-29 | — | — | EP | disclosed |
| US-8779190-B2 | Process for producing sulfur-containing amino acid or salt thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-07-15 | — | — | US | disclosed |
| EP-2609077-A1 | PROCESS FOR PREPARING SULFUR-CONTAINING 2-KETOCARBOXYLATE COMPOUND | Sumitomo Chemical Company Limited (JP) | 2013-07-03 | — | — | EP | disclosed |
| US-20130137897-A1 | PROCESS FOR PREPARING SULFUR-CONTAINING 2-KETOCARBOXYLATE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-30 | — | — | US | disclosed |
| US-20130137896-A1 | PROCESS FOR PREPARING SULFUR-CONTAINING 2-KETOCARBOXYLATE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-30 | — | — | US | disclosed |
| EP-2550251-A1 | PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACID OR SALT THEREOF | Sumitomo Chemical Company, Limited (JP) | 2013-01-30 | — | — | EP | disclosed |
| US-20130012737-A1 | PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACID OR SALT THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-01-10 | — | — | US | disclosed |
| WO-2012026620-A1 | PROCESS FOR PREPARING SULFUR-CONTAINING 2-KETOCARBOXYLATE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-01 | — | — | WO | disclosed |
| WO-2011118849-A1 | PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACID OR SALT THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-09-29 | — | — | WO | disclosed |
| US-20110016582-A1 | Biosynthetic Engineering of Glucosinolates | UNIVERSITY OF COPENHAGEN (DK) | 2011-01-20 | — | — | US | disclosed |
| EP-2257630-A2 | BIOSYNTHETIC ENGINEERING OF GLUCOSINOLATES | University of Copenhagen (DK) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009106985-A2 | BIOSYNTHETIC ENGINEERING OF GLUCOSINOLATES | UNIVERSITY OF COPENHAGEN (DK) | 2009-09-03 | — | — | WO | disclosed |
| US-6977297-B1 | Methods and means for modification of glucosinolates in plants | PLANT BIOSCIENCE LIMITED (GB) | 2005-12-20 | — | — | US | disclosed |
| EP-1032691-A1 | METHODS AND MEANS FOR MODIFICATION OF GLUCOSINOLATES IN PLANTS | Plant Bioscience Limited (GB) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999027120-A1 | METHODS AND MEANS FOR MODIFICATION OF GLUCOSINOLATES IN PLANTS | PLANT BIOSCIENCE LIMITED (GB) | 1999-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137896-A1 | PROCESS FOR PREPARING SULFUR-CONTAINING 2-KETOCARBOXYLATE COMPOUND | HPD, STS, HACL2 | FOLH1 1683/4885MAPK1 3231/4885SLC13A3 2215/4885 |
| US-20130137897-A1 | PROCESS FOR PREPARING SULFUR-CONTAINING 2-KETOCARBOXYLATE COMPOUND | HPD, STS, HAO2 | FOLH1 2035/4885MAPK1 3482/4885SLC13A3 1888/4885 |
| US-20130012737-A1 | PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACID OR SALT THEREOF | CBS, ASS1, TST | FOLH1 3385/4885MAPK1 335/4885SLC13A3 163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.