Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.54 |
| ▸ | PPARG | P37231 | 7/20 | 0.54 |
| ▸ | PPARD | Q03181 | 7/20 | 0.54 |
| ▸ | PPARA | Q07869 | 7/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340793 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL17323034 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL8161852 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL8064431 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL4003102 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL20378734 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL2554930 | 0.97 | — | — | |
| SCHEMBL154914 | 0.90 | — | — | |
| Ammonia Solution, Strong SCHEMBL27490384 | 0.87 | — | — | |
| Methyl Alcohol SCHEMBL28865919 | 0.87 | TSHR (0.56) | TSHRLMNANFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140099354-A1 | BIOPASSIVATING MEMBRANE STABILIZATION BY MEANS OF NITROCARBOXYLIC ACID-CONTAINING PHOSPHOLIPIDS IN PREPARATIONS AND COATINGS | Dietz, Ulrich (DE) | 2014-04-10 | — | — | US | claimed |
| EP-4069412-A1 | ENCAPSULATED ODORANTS BASED ON NATURAL AMINO ACIDS | Symrise AG (DE) | 2022-10-12 | — | — | EP | disclosed |
| WO-2021110273-A1 | ENCAPSULATED ODORANTS BASED ON NATURAL AMINO ACIDS | SYMRISE AG (DE) | 2021-06-10 | — | — | WO | disclosed |
| WO-2021104619-A1 | PARTICULATE PRODUCTS AND METHOD FOR PRODUCTION THEREOF | SYMRISE AG (DE) | 2021-06-03 | — | — | WO | disclosed |
| EP-3826986-A1 | NOVEL ODORANTS HAVING ROSE ODOUR | Symrise AG (DE) | 2021-06-02 | — | — | EP | disclosed |
| CN-106488970-B | Method and use for refining a lipid phase | 德雷伊利林PVG有限责任两合公司 | 2020-12-15 | — | — | CN | disclosed |
| WO-2020020434-A1 | NOVEL ODORANTS HAVING ROSE ODOUR | SYMRISE AG (DE) | 2020-01-30 | — | — | WO | disclosed |
| CN-106459119-B | Device and method for mutually obtaining glycosyl glyceride and glycosphingolipid from rouge sample | 生命纳米科学有限责任两合公司 | 2019-10-25 | — | — | CN | disclosed |
| US-9994464-B2 | Method and devices for de-emulsifying and complexing organic compounds in emulsions | DREI LILIEN PVG GMBH & CO. KG (DE) | 2018-06-12 | — | — | US | disclosed |
| US-9932540-B2 | Method for refining lipid phases, and use | DREI LILIEN PVG GMBH & CO. KG (DE) | 2018-04-03 | — | — | US | disclosed |
| US-9169254-B2 | Spiroimidazolone derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2015-10-27 | — | — | US | disclosed |
| US-9169254-B2 | Spiroimidazolone derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2015-10-27 | — | — | US | disclosed |
| US-9169254-B2 | Spiroimidazolone derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2015-10-27 | — | — | US | disclosed |
| EP-2433940-B1 | SPIROIMIDAZOLONE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2014-09-24 | — | — | EP | disclosed |
| US-20140099354-A1 | BIOPASSIVATING MEMBRANE STABILIZATION BY MEANS OF NITROCARBOXYLIC ACID-CONTAINING PHOSPHOLIPIDS IN PREPARATIONS AND COATINGS | Dietz, Ulrich (DE) | 2014-04-10 | — | — | US | disclosed |
| US-20120270838-A1 | SPIROIMIDAZOLONE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2012-10-25 | — | — | US | disclosed |
| US-20120270838-A1 | SPIROIMIDAZOLONE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2012-10-25 | — | — | US | disclosed |
| US-20120270838-A1 | SPIROIMIDAZOLONE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2012-10-25 | — | — | US | disclosed |
| EP-2433940-A1 | SPIROIMIDAZOLONE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270838-A1 | SPIROIMIDAZOLONE DERIVATIVE | WNK3, REN, SGK3 | TSHR 914/4885LMNA 2006/4885NFKB1 2100/4885 |
| US-20140099354-A1 | BIOPASSIVATING MEMBRANE STABILIZATION BY MEANS OF NITROCARBOXYLIC ACID-CONTAINING PHOSPHOLIPIDS IN PREPARATIONS AND COATINGS | PHOSPHO1, PTDSS1, LIPG | TSHR 4760/4885LMNA 338/4885NFKB1 2838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.