Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7155223

COc1ccc(S(=O)(=O)Nc2ccc(Oc3ccc4cc(C#N)ccc4c3)c(-c3cc(OC)c(OC)cc3C(=O)O)c2)cc1F.O=C(O)C(F)(F)F

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 10/20 0.43
SLC22A12 Q96S37 1/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
PLAU P00749 2/20 0.39
LMNA P02545 1/20 0.38
GPR27 Q9NS67 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7150647 0.90 PLA2G7 (0.44) PLA2G7SLC22A12MEN1KMT2ALMNA
Trifluoroacetic Acid SCHEMBL7157237 0.89 PLA2G7 (0.39) PLA2G7SLC22A12MEN1KMT2APLAU
Trifluoroacetic Acid SCHEMBL7153144 0.89 BRD4 (0.43) PLA2G7
Trifluoroacetic Acid SCHEMBL7155334 0.86 PLA2G7 (0.40) PLA2G7SLC22A12MEN1KMT2A
Trifluoroacetic Acid SCHEMBL6300629 0.81 PLA2G7 (0.44) PLA2G7LMNATSHR
Trifluoroacetic Acid SCHEMBL7154640 0.78 PLA2G7 (0.46) PLA2G7MEN1KMT2ALMNA
Trifluoroacetic Acid SCHEMBL7150670 0.78 PLA2G7 (0.41) PLA2G7SLC22A12
SCHEMBL6294972 0.78 PLAU (0.47) PLA2G7SLC22A12MEN1KMT2APLAU
Trifluoroacetic Acid SCHEMBL6295008 0.78 PLA2G7 (0.46) PLA2G7MEN1KMT2A
Trifluoroacetic Acid SCHEMBL6300704 0.77 PLA2G7 (0.47) PLA2G7MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1312602-A1 Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them Eisai Co., Ltd. (JP) 2003-05-21 EP disclosed