Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 5/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10192141 | 0.82 | MAPT (0.57) | ALDH1A1L3MBTL1MAPTMCOLN3LMNA | |
| SCHEMBL21104531 | 0.79 | KMT2A (0.46) | NPC1RAB9AALDH1A1MAPTTP53 | |
| SCHEMBL12251459 | 0.79 | CA12 (0.48) | ALDH1A1L3MBTL1ESR1MAPTMCOLN3 | |
| SCHEMBL7173210 | 0.78 | HSD17B1 (0.56) | NPC1RAB9AALDH1A1ESR1HSD17B1 | |
| SCHEMBL11356266 | 0.77 | NPC1 (0.49) | NPC1RAB9AALDH1A1L3MBTL1ESR1 | |
| SCHEMBL5623176 | 0.73 | ALDH1A1 (0.71) | NPC1RAB9AALDH1A1L3MBTL1ESR1 | |
| SCHEMBL6295458 | 0.73 | ESR1 (0.50) | NPC1RAB9AALDH1A1L3MBTL1ESR1 | |
| SCHEMBL3721545 | 0.72 | APP (0.45) | NPC1RAB9AALDH1A1ESR1ENPP2 | |
| SCHEMBL10775417 | 0.71 | NPC1 (0.44) | NPC1RAB9AL3MBTL1ESR1APP | |
| SCHEMBL28437320 | 0.71 | NPC1 (0.44) | NPC1RAB9AALDH1A1L3MBTL1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921740-B1 | Electron-receiving compound and thermal recording material | MITSUBISHI PAPER MIILS LTD. (JP) | 2005-07-26 | — | — | US | disclosed |
| US-6579829-B2 | Aromatic sulfonamide compound | MITSUI CHEMICALS, INC. (JP) | 2003-06-17 | — | — | US | disclosed |
| EP-1138517-A2 | Developer composition and heat sensitive recording material | Mitsui Chemicals, Inc. (JP) | 2001-10-04 | — | — | EP | disclosed |