Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ST6GAL1 | P15907 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4450358 | 0.86 | ALDH1A1 (0.54) | ALDH1A1ST6GAL1LMNATHRBMTOR | |
| SCHEMBL7621142 | 0.85 | LMNA (0.67) | ALDH1A1LMNATHRBMTORMDM2 | |
| SCHEMBL1055171 | 0.85 | LMNA (0.67) | ALDH1A1LMNATHRBMTORMDM2 | |
| SCHEMBL1055169 | 0.85 | LMNA (0.67) | ALDH1A1LMNATHRBMTORMDM2 | |
| SCHEMBL13678671 | 0.85 | LMNA (0.66) | ALDH1A1ST6GAL1LMNATHRBMTOR | |
| SCHEMBL441997 | 0.85 | LMNA (0.66) | ALDH1A1ST6GAL1LMNATHRBMTOR | |
| SCHEMBL6361611 | 0.84 | ALDH1A1 (0.49) | ALDH1A1ST6GAL1LMNATHRBMTOR | |
| SCHEMBL7927097 | 0.84 | LMNA (0.48) | ST6GAL1LMNATHRBMTORMDM2 | |
| Hydrochloric Acid SCHEMBL11852550 | 0.84 | LMNA (0.65) | ALDH1A1ST6GAL1LMNATHRBMTOR | |
| SCHEMBL8909227 | 0.84 | P2RY2 (0.53) | ST6GAL1LMNATHRBMTORMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620926-B2 | Composition for use in the generation and purification of oligonucleotide sequences | YALE UNIVERSITY | 2003-09-16 | — | — | US | claimed |
| US-6921818-B2 | Purification of oligomers | YALE UNIVERSITY (US) | 2005-07-26 | — | — | US | disclosed |
| US-20040044190-A1 | Purification of oligomers | SIRNA THERAPEUTICS, INC. | 2004-03-04 | — | — | US | disclosed |
| US-6620926-B2 | Composition for use in the generation and purification of oligonucleotide sequences | YALE UNIVERSITY | 2003-09-16 | — | — | US | disclosed |
| US-20020099182-A1 | Purification of oligomers | YALE UNIVERSITY | 2002-07-25 | — | — | US | disclosed |
| US-6410225-B1 | USING ORGANOSILICON COMPOUNDS | YALE UNIVERSITY | 2002-06-25 | — | — | US | disclosed |
| EP-0989991-A1 | PURIFICATION OF OLIGOMERS | Innovir Laboratories, Inc. (US) | 2000-04-05 | — | — | EP | disclosed |
| WO-1999000402-A1 | PURIFICATION OF OLIGOMERS | INNOVIR LABORATORIES, INC. (US) | 1999-01-07 | — | — | WO | disclosed |