SCHEMBL6302115

SCHEMBL6302115

Cc1ccc(S(=O)(=O)Nc2cc3ccccc3cc2O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.62
ALDH1A1 P00352 5/20 0.62
CYP2C9 P11712 2/20 0.62
CYP2C19 P33261 2/20 0.62
MAPT P10636 2/20 0.62
USP2 O75604 1/20 0.62
POLB P06746 1/20 0.62
NOD2 Q9HC29 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
EP300 Q09472 1/20 0.61
KAT2B Q92831 1/20 0.61
KAT8 Q9H7Z6 1/20 0.61
GAA P10253 3/20 0.60
GFER P55789 1/20 0.60
HKDC1 Q2TB90 1/20 0.59
KEAP1 Q14145 1/20 0.58
NFE2L2 Q16236 1/20 0.58
HTT P42858 2/20 0.56
TSHR P16473 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7571483 0.89 LMNA (0.67) LMNAALDH1A1CYP2C9CYP2C19MAPT
SCHEMBL6295404 0.87 GAA (0.64) LMNAALDH1A1MAPTGAAGFER
SCHEMBL28326534 0.81 HSD17B2 (0.61) LMNAALDH1A1CYP2C9CYP2C19MAPT
SCHEMBL9942107 0.81 HSD17B2 (0.61) LMNAALDH1A1MAPTPOLBL3MBTL1
SCHEMBL23200358 0.81 METAP2 (0.68) LMNAALDH1A1CYP2C9CYP2C19MAPT
SCHEMBL1348234 0.81 LMNA (0.75) LMNAALDH1A1CYP2C9CYP2C19MAPT
SCHEMBL5181886 0.81 HSD17B2 (0.78) LMNAALDH1A1CYP2C9CYP2C19MAPT
SCHEMBL30958861 0.79 CYP2C9 (0.69) LMNAALDH1A1CYP2C9CYP2C19MAPT
SCHEMBL31138226 0.79 FFAR4 (0.64) LMNAALDH1A1CYP2C9CYP2C19MAPT
SCHEMBL23200344 0.79 FFAR4 (0.64) LMNAALDH1A1CYP2C9CYP2C19MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6921740-B1 Electron-receiving compound and thermal recording material MITSUBISHI PAPER MIILS LTD. (JP) 2005-07-26 US disclosed