Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.67 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 4/20 | 0.61 |
| ▸ | CA9 | Q16790 | 4/20 | 0.61 |
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | CA4 | P22748 | 2/20 | 0.61 |
| ▸ | CA7 | P43166 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6302115 | 0.89 | LMNA (0.62) | LMNAALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL30958861 | 0.86 | CYP2C9 (0.69) | LMNAALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL23200358 | 0.85 | METAP2 (0.68) | LMNAALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL7577515 | 0.85 | SMN1; SMN2 (0.65) | LMNAALDH1A1MAPTKEAP1TSHR | |
| SCHEMBL2068526 | 0.85 | LMNA (0.82) | LMNAALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL7595414 | 0.83 | ALDH1A1 (0.70) | LMNAALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL31138226 | 0.83 | FFAR4 (0.64) | LMNAALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL15457558 | 0.83 | GAA (0.59) | LMNAALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL23200344 | 0.83 | FFAR4 (0.64) | LMNAALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL5955421 | 0.83 | CYP2C9 (0.61) | LMNAALDH1A1CYP2C9CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |