Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22563058 | 0.76 | TRPV4 (0.42) | KDM4EGAAALDH1A1MAP2K1LRRK2 | |
| SCHEMBL1797379 | 0.70 | TRPV4 (0.59) | TRPV4CYP11B1CYP11B2 | |
| SCHEMBL21897870 | 0.70 | IMPDH2 (0.37) | KDM4EGAAALDH1A1CXCR2TRPV4 | |
| SCHEMBL17146959 | 0.70 | LOXL2 (0.41) | KDM4EGAAALDH1A1CXCR2LRRK2 | |
| SCHEMBL28200176 | 0.70 | KDM4E (0.40) | KDM4EGAAALDH1A1CXCR2MEN1 | |
| Hydrochloric Acid SCHEMBL20984963 | 0.68 | KDM4E (0.39) | KDM4EGAAALDH1A1CXCR2MEN1 | |
| Bromide SCHEMBL20984939 | 0.68 | KDM4E (0.39) | KDM4EGAAALDH1A1CXCR2MEN1 | |
| SCHEMBL11313465 | 0.67 | CA1 (0.37) | KDM4EGAAALDH1A1MAP2K1CXCR2 | |
| SCHEMBL924361 | 0.67 | TRPV4 (0.45) | ALDH1A1TRPV4CYP11B1CYP11B2 | |
| SCHEMBL28249040 | 0.66 | SCN1A (0.36) | KDM4EALDH1A1MAP2K1LRRK2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875764-B1 | Urea and thiourea compounds useful for treatment of coccidiosis | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-04-05 | — | — | US | disclosed |