Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | MYOC | Q99972 | 1/20 | 0.57 |
| ▸ | BAZ1A | Q9NRL2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.54 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.54 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.54 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6295866 | 0.87 | ALDH1A1 (0.57) | MEN1KMT2AMAPTNPC1NPSR1 | |
| SCHEMBL1177730 | 0.82 | MEN1 (1.00) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL6302157 | 0.82 | MEN1 (1.00) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL5657895 | 0.80 | NPC1 (0.74) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL9613320 | 0.78 | MEN1 (0.56) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL6302417 | 0.77 | MEN1 (0.89) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL3460442 | 0.76 | MEN1 (0.79) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL11055960 | 0.76 | MEN1 (0.85) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL27968750 | 0.76 | MEN1 (0.72) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL8371944 | 0.75 | MEN1 (0.66) | MEN1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875764-B1 | Urea and thiourea compounds useful for treatment of coccidiosis | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-04-05 | — | — | US | disclosed |
| EP-1224165-A1 | NOVEL COMPOUNDS | New Pharma Research Sweden AB (SE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001030749-A1 | NOVEL COMPOUNDS | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2001-05-03 | — | — | WO | disclosed |