Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 14/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630149 | 0.89 | POLB (0.49) | BDKRB1POLBKCNQ1L3MBTL1ITGAV | |
| SCHEMBL1381715 | 0.89 | POLB (0.49) | BDKRB1POLBKCNQ1L3MBTL1ITGAV | |
| SCHEMBL629859 | 0.87 | BDKRB1 (0.44) | BDKRB1POLBKCNQ1KMT2AL3MBTL1 | |
| SCHEMBL629653 | 0.76 | POLB (0.53) | BDKRB1POLBKCNQ1KMT2AL3MBTL1 | |
| SCHEMBL1383184 | 0.76 | POLB (0.53) | BDKRB1POLBKCNQ1KMT2AL3MBTL1 | |
| SCHEMBL631251 | 0.75 | ALDH1A1 (0.49) | L3MBTL1 | |
| SCHEMBL631034 | 0.75 | KCNQ1 (0.44) | BDKRB1POLBKCNQ1MEN1KMT2A | |
| SCHEMBL8266730 | 0.75 | POLB (0.48) | BDKRB1POLBKCNQ1ITGAV | |
| SCHEMBL1384096 | 0.74 | POLB (0.53) | BDKRB1POLBKCNQ1L3MBTL1 | |
| SCHEMBL631527 | 0.74 | POLB (0.53) | BDKRB1POLBKCNQ1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | claimed |