Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ1 | P51787 | 1/20 | 0.44 |
| ▸ | BDKRB1 | P46663 | 12/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631253 | 0.90 | BDKRB1 (0.42) | KCNQ1BDKRB1POLBCACNA1B | |
| SCHEMBL1384581 | 0.89 | POLB (0.52) | KCNQ1BDKRB1POLBHCRTR1HCRTR2 | |
| SCHEMBL630359 | 0.89 | POLB (0.52) | KCNQ1BDKRB1POLBHCRTR1HCRTR2 | |
| SCHEMBL630823 | 0.84 | KCNQ1 (0.49) | KCNQ1BDKRB1POLBHCRTR1HCRTR2 | |
| SCHEMBL631181 | 0.83 | LMNA (0.44) | KCNQ1BDKRB1POLBHCRTR1HCRTR2 | |
| SCHEMBL630680 | 0.83 | KCNQ1 (0.48) | KCNQ1BDKRB1POLBHCRTR1HCRTR2 | |
| SCHEMBL631050 | 0.83 | KCNQ1 (0.47) | KCNQ1BDKRB1HCRTR1HCRTR2KMT2A | |
| SCHEMBL630671 | 0.83 | POLB (0.46) | KCNQ1BDKRB1POLBHCRTR1HCRTR2 | |
| SCHEMBL631046 | 0.81 | ITGB1 (0.53) | KCNQ1BDKRB1POLBHCRTR1HCRTR2 | |
| SCHEMBL631047 | 0.81 | ITGB1 (0.53) | KCNQ1BDKRB1POLBHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | claimed |