Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 3/20 | 0.63 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383454 | 1.00 | ITGB1 (0.63) | ITGB1ITGA5LMNAMEN1KMT2A | |
| SCHEMBL630266 | 0.86 | ITGB1 (0.49) | ITGB1ITGA5LMNAMEN1KMT2A | |
| SCHEMBL7069030 | 0.82 | ITGB1 (0.74) | ITGB1ITGA5MEN1KMT2AALDH1A1 | |
| SCHEMBL631739 | 0.81 | TDP1 (0.56) | ITGB1ITGA5LMNAALDH1A1MAPK1 | |
| SCHEMBL6709558 | 0.79 | ITGB1 (0.69) | ITGB1ITGA5MEN1KMT2AALDH1A1 | |
| SCHEMBL1381494 | 0.78 | FKBP1A (0.55) | ITGB1ITGA5LMNAALDH1A1MAPK1 | |
| SCHEMBL8268070 | 0.77 | ITGB1 (0.65) | ITGB1ITGA5LMNAALDH1A1MAPK1 | |
| SCHEMBL1379870 | 0.77 | ITGB1 (0.65) | ITGB1ITGA5LMNAALDH1A1MAPK1 | |
| SCHEMBL629765 | 0.77 | ITGB1 (0.65) | ITGB1ITGA5LMNAALDH1A1MAPK1 | |
| SCHEMBL18339181 | 0.77 | ITGB1 (1.00) | ITGB1ITGA5LMNAMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | claimed |
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | disclosed |