Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630767 | 0.88 | ITGB1 (0.46) | ITGB1ITGA5LMNAALDH1A1PKM | |
| SCHEMBL630237 | 0.86 | ITGB1 (0.63) | ITGB1ITGA5LMNAALDH1A1KMT2A | |
| SCHEMBL631469 | 0.86 | ALDH1A1 (0.44) | ITGB1ITGA5LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL1383454 | 0.86 | ITGB1 (0.63) | ITGB1ITGA5LMNAALDH1A1KMT2A | |
| SCHEMBL630786 | 0.82 | TDP1 (0.46) | LMNAALDH1A1PKMTDP1MAPK1 | |
| SCHEMBL631343 | 0.80 | PKM (0.43) | LMNAALDH1A1SMN1; SMN2PKMTDP1 | |
| SCHEMBL631194 | 0.79 | ITGB1 (0.47) | ITGB1ITGA5LMNAALDH1A1KMT2A | |
| SCHEMBL631775 | 0.77 | LMNA (0.47) | LMNAALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL631233 | 0.77 | FKBP1A (0.46) | ITGB1ITGA5LMNAALDH1A1PKM | |
| SCHEMBL630023 | 0.76 | AKR1C3 (0.44) | ITGB1ITGA5LMNAALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | claimed |