Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.57 |
| ▸ | ITGAV | P06756 | 18/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.48 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.38 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6308297 | 0.98 | ITGB3 (0.59) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| Trifluoroacetic Acid SCHEMBL6300648 | 0.95 | ITGB3 (0.53) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL6301697 | 0.95 | ITGB3 (0.52) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| Trifluoroacetic Acid SCHEMBL6300360 | 0.90 | ITGB3 (0.48) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL6300654 | 0.86 | ITGB3 (0.43) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL6308242 | 0.85 | ITGB3 (0.48) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL4715705 | 0.81 | ITGB3 (0.55) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL6300365 | 0.81 | TRPM8 (0.41) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| Trifluoroacetic Acid SCHEMBL6307546 | 0.81 | ITGB3 (0.45) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL4718120 | 0.81 | ITGB3 (0.54) | ITGB3ITGAVITGA2BITGB5ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846833-B2 | Vitronectin receptor antagonist bicyclic compounds, preparation method and compositions containing same | LES LABORATORIES SERVIER (FR) | 2005-01-25 | — | — | US | disclosed |
| EP-1268429-B1 | VITRONECTIN RECEPTOR ANTAGONIST BICYCLIC COMPOUNDS, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2004-08-18 | — | — | EP | disclosed |