Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.43 |
| ▸ | ITGAV | P06756 | 15/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.36 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6300365 | 0.95 | TRPM8 (0.41) | ITGB3ITGAVITGA2BTRPM8ITGB5 | |
| Trifluoroacetic Acid SCHEMBL6300648 | 0.88 | ITGB3 (0.53) | ITGB3ITGAVITGA2BTRPM8ITGB5 | |
| SCHEMBL6307550 | 0.87 | TRPM8 (0.38) | ITGB3ITGAVITGA2BTRPM8ITGB5 | |
| SCHEMBL6302598 | 0.86 | ITGB3 (0.57) | ITGB3ITGAVITGA2BTRPM8ITGB5 | |
| SCHEMBL6308297 | 0.85 | ITGB3 (0.59) | ITGB3ITGAVITGA2BTRPM8ITGB5 | |
| Trifluoroacetic Acid SCHEMBL6300360 | 0.83 | ITGB3 (0.48) | ITGB3ITGAVITGA2BTRPM8ITGB5 | |
| SCHEMBL6302652 | 0.82 | BDKRB1 (0.38) | ITGB3ITGAV | |
| SCHEMBL6301697 | 0.81 | ITGB3 (0.52) | ITGB3ITGAVITGA2BTRPM8ITGB5 | |
| SCHEMBL6302566 | 0.81 | ALDH1A1 (0.33) | — | |
| Trifluoroacetic Acid SCHEMBL6307546 | 0.75 | ITGB3 (0.45) | ITGB3ITGAVITGA2BTRPM8ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846833-B2 | Vitronectin receptor antagonist bicyclic compounds, preparation method and compositions containing same | LES LABORATORIES SERVIER (FR) | 2005-01-25 | — | — | US | disclosed |