Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 6/20 | 0.74 |
| ▸ | MAOA | P21397 | 6/20 | 0.69 |
| ▸ | MAOB | P27338 | 2/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.63 |
| ▸ | SDHA | P31040 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6302773 | 1.00 | CALML3 (0.74) | CALML3MAOAMAOBPTGS1SDHA | |
| SCHEMBL1394066 | 0.91 | CALML3 (0.62) | CALML3MAOAMAOBPTGS1SDHA | |
| SCHEMBL1393760 | 0.91 | CALML3 (0.62) | CALML3MAOAMAOBPTGS1SDHA | |
| SCHEMBL1393541 | 0.90 | CALML3 (0.61) | CALML3MAOAMAOBPTGS1SDHA | |
| SCHEMBL1393455 | 0.90 | CALML3 (0.61) | CALML3MAOAMAOBPTGS1SDHA | |
| SCHEMBL30063940 | 0.90 | MAOA (0.69) | CALML3MAOAMAOBPTGS1SDHA | |
| SCHEMBL7944586 | 0.90 | MAOA (0.69) | CALML3MAOAMAOBPTGS1SDHA | |
| SCHEMBL1393698 | 0.90 | MAOA (0.69) | CALML3MAOAMAOBPTGS1SDHA | |
| SCHEMBL3328443 | 0.90 | MAOA (0.76) | CALML3MAOAMAOBPTGS1SDHA | |
| SCHEMBL3328441 | 0.90 | MAOA (0.76) | CALML3MAOAMAOBPTGS1SDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3176626-B2 | — | — | 2001-06-18 | — | — | JP | claimed |
| EP-0610265-B1 | SUBSTITUTED ARYL- AND HETEROARYLPHENYLOXAZOLIDINONES USEFUL AS ANTIBACTERIAL AGENTS | UPJOHN CO (US) | 1996-12-27 | — | — | EP | claimed |
| US-5565571-A | BACTERICIDES | THE UPJOHN COMPANY (US) | 1996-10-15 | — | — | US | claimed |
| EP-0610265-A1 | SUBSTITUTED ARYL- AND HETEROARYLPHENYLOXAZOLIDINONES USEFUL AS ANTIBACTERIAL AGENTS. | UPJOHN CO (US) | 1994-08-17 | — | — | EP | claimed |
| WO-1993009103-A1 | SUBSTITUTED ARYL- AND HETEROARYLPHENYLOXAZOLIDINONES USEFUL AS ANTIBACTERIAL AGENTS | THE UPJOHN COMPANY (US) | 1993-05-13 | — | — | WO | claimed |
| US-6875871-B2 | Oxazolidinone photoaffinity probes | PHARMACIA & UPJOHN COMPANY (US) | 2005-04-05 | — | — | US | disclosed |
| US-6861433-B2 | Oxazolidinone photoaffinity probes | PHARMACIA & UPJOHN COMPANY (US) | 2005-03-01 | — | — | US | disclosed |
| US-6858635-B2 | Oxazolidinone photoaffinity probes | PHARMACIA & UPJOHN COMPANY (US) | 2005-02-22 | — | — | US | disclosed |
| EP-1386153-A2 | OXAZOLIDINONE PHOTOAFFINITY PROBES, USES AND COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 2004-02-04 | — | — | EP | disclosed |
| US-20030232008-A1 | Oxazolidinone photoaffinity probes | PHARMACIA & UPJOHN COMPANY | 2003-12-18 | — | — | US | disclosed |
| US-20030232840-A1 | Oxazolidinone photoaffinity probes | PHARMACIA & UPJOHN COMPANY | 2003-12-18 | — | — | US | disclosed |
| EP-1368326-A2 | OXAZOLIDINONE PHOTOAFFINITY PROBES | PHARMACIA & UPJOHN COMPANY (US) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002048139-A2 | OXAZOLIDINONE PHOTOAFFINITY PROBES | PHARMACIA & UPJOHN COMPANY (US) | 2002-06-20 | — | — | WO | disclosed |
| WO-1999033839-A1 | CEPHEM DERIVATIVES AND A METHOD FOR PRODUCING THE COMPOUNDS AND AN ANTIBACTERIAL COMPOSITION CONTAINING THE COMPOUNDS | CHEIL JEDANG CORPORATION (KR) | 1999-07-08 | — | — | WO | disclosed |
| US-5654435-A | BACTERICIDES | PHARMACIA & UPJOHN COMPANY (US) | 1997-08-05 | — | — | US | disclosed |
| US-5654428-A | BACTERICIDES | PHARMACIA & UPJOHN COMPANY (US) | 1997-08-05 | — | — | US | disclosed |
| EP-0610265-B1 | SUBSTITUTED ARYL- AND HETEROARYLPHENYLOXAZOLIDINONES USEFUL AS ANTIBACTERIAL AGENTS | UPJOHN CO (US) | 1996-12-27 | — | — | EP | disclosed |
| US-5565571-A | BACTERICIDES | THE UPJOHN COMPANY (US) | 1996-10-15 | — | — | US | disclosed |
| EP-0610265-A1 | SUBSTITUTED ARYL- AND HETEROARYLPHENYLOXAZOLIDINONES USEFUL AS ANTIBACTERIAL AGENTS. | UPJOHN CO (US) | 1994-08-17 | — | — | EP | disclosed |
| WO-1993009103-A1 | SUBSTITUTED ARYL- AND HETEROARYLPHENYLOXAZOLIDINONES USEFUL AS ANTIBACTERIAL AGENTS | THE UPJOHN COMPANY (US) | 1993-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232840-A1 | Oxazolidinone photoaffinity probes | SLC18A1, DDT, MC2R | CALML3 1619/4885MAOA 358/4885MAOB 219/4885 |
| US-20030232008-A1 | Oxazolidinone photoaffinity probes | SLC18A1, DDT, MC2R | CALML3 1619/4885MAOA 358/4885MAOB 219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.