Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 5/20 | 0.66 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.61 |
| ▸ | CTSL | P07711 | 2/20 | 0.55 |
| ▸ | TACR1 | P25103 | 2/20 | 0.54 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3132344 | 1.00 | CTSB (0.66) | CTSBCTRB1CTSLTACR1CAPN1 | |
| SCHEMBL3337955 | 1.00 | CTSB (0.66) | CTSBCTRB1CTSLTACR1CAPN1 | |
| SCHEMBL3132335 | 0.94 | CTSB (0.60) | CTSBCTRB1CTSLTACR1CAPN1 | |
| SCHEMBL7436543 | 0.94 | CTSB (0.60) | CTSBCTRB1CTSLTACR1CAPN1 | |
| SCHEMBL14884508 | 0.93 | CTSB (0.59) | CTSBCTRB1CTSLTACR1CTSS | |
| SCHEMBL7214968 | 0.92 | CTSB (0.58) | CTSBCTRB1CTSLCAPN1CTSS | |
| SCHEMBL3132690 | 0.90 | ATM (0.61) | CTSBCTRB1CTSLCTSS | |
| SCHEMBL13725177 | 0.90 | CTSB (0.62) | CTSBCTRB1CTSL | |
| SCHEMBL2736217 | 0.89 | CTSL (0.62) | CTSBCTRB1CTSLTACR1CTSS | |
| SCHEMBL7310419 | 0.89 | CTSL (0.62) | CTSBCTRB1CTSLTACR1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 329 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670305-B1 | PROCESS FOR PRODUCING 3-AMINO-2-HYDROXY-1-PROPANOL DERIVATIVE | KANEKA CORP (JP) | 1998-05-20 | — | — | EP | claimed |
| US-5744630-A | Method of producing 3-amino-2-hydroxy-1-propanol derivatives | KANEKA CORPORATION (JP) | 1998-04-28 | — | — | US | claimed |
| EP-0601486-B1 | Cis-epoxide derivatives useful as irreversible HIV protease inhibitors and process and intermediates for their preparation | LUCKY LTD (KR) | 1997-10-29 | — | — | EP | claimed |
| EP-0670305-A1 | PROCESS FOR PRODUCING 3-AMINO-2-HYDROXY-1-PROPANOL DERIVATIVE | KANEKA CORPORATION (JP) | 1995-09-06 | — | — | EP | claimed |
| EP-0601486-A1 | Cis-epoxide derivatives useful as irreversible HIV protease inhibitors and process and intermediates for their preparation | LUCKY LTD. (KR) | 1994-06-15 | — | — | EP | claimed |
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | claimed |
| EP-0288176-A1 | Tyrosine derivatives and use thereof | AJINOMOTO CO., INC. (JP) | 1988-10-26 | — | — | EP | claimed |
| US-4650785-A | ORAL ADMINISTRATION OF INSULIN | AJINOMOTO COMPANY INCOPORATED (JP) | 1987-03-17 | — | — | US | claimed |
| US-4548926-A | RENIN INHIBITOR | SANKYO COMPANY LIMITED (JP) | 1985-10-22 | — | — | US | claimed |
| EP-0128762-A2 | New hypotensive peptides, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1984-12-19 | — | — | EP | claimed |
| EP-0093551-A2 | Pharmaceutical composition | AJINOMOTO CO., INC. (JP) | 1983-11-09 | — | — | EP | claimed |
| US-4401594-A | PROTEOLYTIC ENZYME INHIBIJTORS; CARDIOVASCULAR AND MUSCULAR DISORDERS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-08-30 | — | — | US | claimed |
| JP-10087639-A | — | — | None | — | — | JP | disclosed |
| JP-10081653-A | — | — | None | — | — | JP | disclosed |
| JP-58189121-A | — | — | None | — | — | JP | disclosed |
| JP-62026273-A | — | — | None | — | — | JP | disclosed |
| EP-0125056-A2 | Condensed, seven-membered ring compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1984-11-14 | — | — | EP | disclosed |
| EP-0093551-A2 | Pharmaceutical composition | AJINOMOTO CO., INC. (JP) | 1983-11-09 | — | — | EP | disclosed |
| EP-0093551-A2 | Pharmaceutical composition | AJINOMOTO CO., INC. (JP) | 1983-11-09 | — | — | EP | disclosed |
| JP-S58189121-A | ACTIVATOR FOR ADMINISTRATION OF INSULIN | AJINOMOTO CO INC | 1983-11-04 | — | — | JP | disclosed |