Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 8/20 | 0.48 |
| ▸ | SSTR1 | P30872 | 6/20 | 0.48 |
| ▸ | SSTR2 | P30874 | 6/20 | 0.48 |
| ▸ | SSTR3 | P32745 | 6/20 | 0.48 |
| ▸ | SSTR5 | P35346 | 6/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | CDC25B | P30305 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6303403 | 0.85 | ALDH1A1 (0.39) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL6298727 | 0.83 | SSTR1 (0.41) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL6297123 | 0.83 | PTPN1 (0.42) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL6298852 | 0.82 | SSTR1 (0.48) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL6304183 | 0.80 | SSTR1 (0.48) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL14490124 | 0.79 | PTPN1 (0.44) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL14490123 | 0.78 | SSTR1 (0.46) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL22721951 | 0.77 | SSTR1 (0.41) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL8992070 | 0.77 | SSTR1 (0.41) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL6218211 | 0.76 | SSTR4 (0.62) | SSTR4SSTR1SSTR2SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878690-B2 | Compounds and methods | PHARMAXIS PTY LTD. (AU) | 2005-04-12 | — | — | US | disclosed |
| EP-1301522-A4 | NOVEL COMPOUNDS AND METHODS | PHARMAXIS PTY LTD (AU) | 2004-04-14 | — | — | EP | disclosed |
| US-20030176363-A1 | Novel compounds and methods | PHARMAXIS PTY LTD. (AU) | 2003-09-18 | — | — | US | disclosed |
| EP-1301522-A1 | NOVEL COMPOUNDS AND METHODS | Pharmaxis Pty Ltd (AU) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002004472-A1 | NOVEL COMPOUNDS AND METHODS | PHARMAXIS PTY LTD (AU) | 2002-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176363-A1 | Novel compounds and methods | NFATC1, CD4, CCR5 | SSTR4 4487/4885SSTR1 4765/4885SSTR2 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.