SCHEMBL630386

SCHEMBL630386

Cc1ccc(C)c(N=Nc2cc(C)c(N/N=C3\C(=O)C=Cc4ccccc43)cc2C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.40
ALDH1A1 P00352 5/20 0.40
RAB9A P51151 4/20 0.40
NPC1 O15118 4/20 0.40
GAA P10253 3/20 0.40
MAPK1 P28482 2/20 0.34
KMT2A Q03164 8/20 0.33
MEN1 O00255 7/20 0.33
TDP1 Q9NUW8 4/20 0.33
ALOX12 P18054 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HSD17B10 Q99714 3/20 0.32
KDM4E B2RXH2 2/20 0.32
HPGD P15428 2/20 0.32
POLB P06746 2/20 0.32
LMNA P02545 1/20 0.32
BCHE P06276 1/20 0.32
PTPRC P08575 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11973972 1.00 MAPT (0.40) MAPTALDH1A1RAB9ANPC1GAA
SCHEMBL11974570 0.91 MAPT (0.34) MAPTALDH1A1RAB9ANPC1GAA
SCHEMBL630098 0.91 MAPT (0.34) MAPTALDH1A1RAB9ANPC1GAA
SCHEMBL2312130 0.84 MAPT (0.56) MAPTALDH1A1RAB9ANPC1GAA
SCHEMBL11876770 0.84 MAPT (0.56) MAPTALDH1A1RAB9ANPC1GAA
SCHEMBL19322469 0.78 TP53 (0.42) MAPTALDH1A1RAB9ANPC1GAA
SCHEMBL11877584 0.78 TP53 (0.42) MAPTALDH1A1RAB9ANPC1GAA
SCHEMBL332277 0.78 TP53 (0.42) MAPTALDH1A1RAB9ANPC1GAA
SCHEMBL11877590 0.78 TP53 (0.42) MAPTALDH1A1RAB9ANPC1GAA
SCHEMBL2389884 0.76 ALDH1A1 (0.42) MAPTALDH1A1RAB9ANPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070916-A Application of arteannuin with double functions in promoting liver cell maturation and relieving liver lipid metabolism dysfunction 广州市第一人民医院(广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院) 2026-05-22 CN disclosed
US-20250057808-A1 COMPOSITION COMPRISING BETA LACTAM FOR TREATING ALCOHOL DEPENDENCE AND ALCOHOL ASSOCIATED DISEASES OR CONDITIONS UNIVERSITY OF TOLEDO 2025-02-20 US disclosed
EP-4380904-A1 MIXED-MATRIX COMPOSITE INTEGRATED FIBER OPTIC CO2 SENSOR Battelle Memorial Institute (US) 2024-06-12 EP disclosed
US-12005090-B2 Probiotic composition including lactic acid bacterial strains and use of at least one of such strains GLAC BIOTECH CO., LTD. (TW) 2024-06-11 US disclosed
US-20230399422-A1 ADDITIVE MANUFACTURING POLYELECTROLYTE RESIN AND ADDITIVELY MANUFACTURING GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE 2023-12-14 US disclosed
CN-116217663-A Antioxidant polypeptide KFTCAP derived from haematococcus pluvialis, preparation method and application 华南农业大学 2023-06-06 CN disclosed
CN-116121190-A Induction culture solution for inducing stem cells into midbrain dopaminergic neuron precursor cells, application thereof and induction method 同济大学 2023-05-16 CN disclosed
US-11583373-B2 Coloured curable composition for additive manufacturing processes, 3-dim composite article and use thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-02-21 US disclosed
US-20230039427-A1 Mixed-matrix composite integrated fiber optic CO2 sensor BATTELLE MEMORIAL INSTITUTE 2023-02-09 US disclosed
WO-2023015044-A1 MIXED-MATRIX COMPOSITE INTEGRATED FIBER OPTIC CO2 SENSOR BATTELLE MEMORIAL INSTITUTE (US) 2023-02-09 WO disclosed
EP-1878756-A1 Labeled tackifiers National Starch and Chemical Investment Holding Corporation (US) 2008-01-16 EP disclosed
US-20080009573-A1 Labeled tackifiers NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORP. 2008-01-10 US disclosed
US-20070154621-A1 METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2007-07-05 US disclosed
WO-2006136423-A2 MEDICAMENT FOR THE TREATMENT OF IMPAIRED GLUCOSE METABOLISM DSM IP ASSETS B.V. (NL) 2006-12-28 WO disclosed
WO-2006136429-A1 COMPOUNDS FOR THE TREATMENT OF NON-AUTOIMMUNE TYPE 2 DIABETES MELLITUS AND/OR SYNDROME X DSM IP ASSETS B.V. (NL) 2006-12-28 WO disclosed
US-20050197634-A1 Methods for coating and impregnating medical devices with antiseptic compositions BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2005-09-08 US disclosed
EP-0481519-B1 Standard samples and methods of instrumental measurement of ASTM color of petroleum products using said samples NIPPON PETROLEUM REFINING CO (JP) 1995-01-11 EP disclosed
US-5381227-A Solutions of azo and anthraquinone dyes NIPPON PETROLEUM REFINING CO., LTD. (JP) 1995-01-10 US disclosed
US-5139330-A Oxidation resistance, color stability NIPPON PETROLEUM REFINING CO., LTD. (JP) 1992-08-18 US disclosed
EP-0481519-A1 Standard samples and methods of instrumental measurement of ASTM color of petroleum products using said samples NIPPON PETROLEUM REFINING COMPANY, Ltd. (JP) 1992-04-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250057808-A1 COMPOSITION COMPRISING BETA LACTAM FOR TREATING ALCOHOL DEPENDENCE AND ALCOHOL ASSOCIATED DISEASES OR CONDITIONS ADH1A, ADH1C, SLC10A1 MAPT 1038/4885ALDH1A1 41/4885RAB9A 822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.