Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.42 |
| ▸ | GOPC | Q9HD26 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.32 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6296791 | 0.74 | CFTR (0.42) | CFTRGOPCALDH1A1KMT2ARAB9A | |
| SCHEMBL14973844 | 0.70 | ALDH1A1 (0.42) | CFTRGOPCALDH1A1MAPK1KDM1A | |
| SCHEMBL1923692 | 0.69 | IDO1 (0.46) | — | |
| SCHEMBL31490422 | 0.69 | IDO1 (0.46) | — | |
| SCHEMBL5394456 | 0.69 | CFTR (0.38) | CFTRGOPCALDH1A1KMT2ASLC6A3 | |
| SCHEMBL5394469 | 0.69 | CFTR (0.38) | CFTRGOPCALDH1A1KMT2ASLC6A3 | |
| SCHEMBL7212942 | 0.67 | ALDH1A1 (0.53) | CFTRGOPCALDH1A1KMT2AMAPK1 | |
| SCHEMBL868869 | 0.67 | CFTR (0.68) | CFTRGOPCALDH1A1KMT2AMAPK1 | |
| SCHEMBL6363384 | 0.67 | CFTR (0.52) | CFTRGOPCALDH1A1KMT2AMAPK1 | |
| SCHEMBL695560 | 0.65 | ALDH1A1 (0.42) | CFTRGOPCALDH1A1MAPK1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6946531-B2 | Low molecular weight ethylene interpolymers and polymerization process | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-09-20 | — | — | US | disclosed |
| EP-1389215-B1 | 3-ARYL-SUBSTITUTED CYCLOPENTADIENYL METAL COMPLEXES AND POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2005-06-15 | — | — | EP | disclosed |
| US-6825147-B2 | (3,4-DIPHENYLCYCLOPENTADIEN-1-YL)DIMETHYL(T-BUTYLAMIDO) -SILANETITANIUM DICHLORIDE, FOR EXAMPLE; FOR COPOLYMERIZATION OF ETHYLENE AND STYRENE | DOW GLOBAL TECHNOLOGIES INC. | 2004-11-30 | — | — | US | disclosed |
| US-20040092680-A1 | Addition copolymerization using titanium complexes comprising a 3-aryl-substituted cyclopentadienyl ring as polymerization catalyst | DOW GLOBAL TECHNOLOGIES LLC | 2004-05-13 | — | — | US | disclosed |
| EP-1389215-A1 | 3-ARYL-SUBSTITUTED CYCLOPENTADIENYL METAL COMPLEXES AND POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-02-18 | — | — | EP | disclosed |
| US-20020183464-A1 | 3-aryl-substituted cyclopentadienyl metal complexes and polymerization process | DOW GLOBAL TECHNOLOGIES LLC | 2002-12-05 | — | — | US | disclosed |
| WO-2002092610-A1 | 3-ARYL-SUBSTITUTED CYCLOPENTADIENYL METAL COMPLEXES AND POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2002-11-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183464-A1 | 3-aryl-substituted cyclopentadienyl metal complexes and polymerization process | SOD1, AOC3, PPOX | CFTR 4534/4885GOPC 244/4885ALDH1A1 2180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.